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FASUDIL

FASUDIL Suppliers list
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:1-(5-Isoquinolinesulfonyl)-1H-hexahydro-1,4-diazepine, Dihydrochloride
CAS:103745-39-7
Package:250Mg,25Mg
Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel:86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email:67055399@qq.com
Products Intro: Product Name:Fasudil hydrochloride
CAS:103745-39-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name:Energy Chemical  
Tel:021-58432009 / 400-005-6266
Email:info@energy-chemical.com
Products Intro: Product Name:0
CAS:103745-39-7
Purity:99% Package:1g,5g
Company Name:Ascent Scientific  
Tel:4401179829988
Email:customerservice@ascentscientific.co.uk
Products Intro: Product Name:HA-1077;Fasudil
CAS:103745-39-7
Purity:>98% Package:10mg;50mg Remarks:ROCK2 inhibitor
Company Name:Jia Xing Isenchem Co.,Ltd  
Tel:0573-85280080 18267390595
Email:isenchem@163.com,QQ:1404038297
Products Intro: CAS:103745-39-7
Purity:98% HPLC Package:25g,100g,500g,1kg
FASUDIL Basic information
Product Name:FASUDIL
Synonyms:FASUDIL;1-(5-ISOQUINOLINE-SULFONYL)-HOMOPIPERAZINE;at877;hexahydro-1-(5-isoquinolinylsulfonyl)-1h-4-diazepine;HA-1077 DIHYDROCHLORIDE NOVEL VASODILATO R AGE;HA 1077, DIHYDROCHLORIDE, 99+%;Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine;HA-1077：Eril
CAS:103745-39-7
MF:C14H17N3O2S
MW:291.37
EINECS:
Product Categories:Protein Kinase Inhibitors and Activators;Protein Kinase;Signalling;Angiogenesis and Metastasis;Intracellular signaling;APIs;ERIL
Mol File:103745-39-7.mol
FASUDIL Structure
FASUDIL Chemical Properties
storage temp. Store at RT
solubility H2O: >200 mg/mL
form solid
color white
CAS DataBase Reference103745-39-7(CAS DataBase Reference)
Safety Information
WGK Germany 3
RTECS HM4031166
MSDS Information
FASUDIL Usage And Synthesis
Chemical PropertiesWhite Crystalline Solid
Usagevasodilator (cerebral), Ca antagonist
UsageA potent calcium antagonist vasodilator which is considered to act by employing different mechanisms from the usual calcium channel blockers since it inhibits (1) calcium ionophore A23187 induced co ntraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellular space. Also reported to potently inhibit Rho- associated Kinase (ROCK IC50= 10.7 uM).
Biological ActivityCyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM). Ca2+ antagonist and vasodilator. Also inhibits proliferation of vascular smooth muscle cells.
FASUDIL Preparation Products And Raw materials
Raw materialsIsoquinoline
Tag:FASUDIL(103745-39-7) Related Product Information
HA1077 (Fasudil) 1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride, Fasudil dihydrochloride Fasudil Monohydrochloride,FASUDIL HCL,FASUDIL HYDROCHLORIDE,FASUDIL DIHYDROCHLORIDE H-1152Glycyl, Dihydrochloride FASUDIL 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE (S)-(+)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLYNYL)SULFONYL]HOMOPIPERAZINE