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H-1152Glycyl, Dihydrochloride

H-1152Glycyl, Dihydrochloride Suppliers list
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:H-1152 Glycyl Dihydrochloride
CAS:913844-45-8
Package:10Mg,1Mg
Company Name:VDM Biochemicals   
Tel:0330-2528181
Email:sales@vdmbio.com
Products Intro: Product Name:Glycyl-H 1152 dihydrochloride
CAS:913844-45-8
Company Name:Chemsky（shanghai）International Co.,Ltd.  
Tel:021-50135380
Email:shchemsky@sina.com
Products Intro: Product Name:H-1152 Glycyl Dihydrochloride
CAS:913844-45-8
Purity:98%
Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd  
Tel:+86-571-82693216/13216174607
Email:info@chemyuhao.com
Products Intro: CAS:913844-45-8
Company Name:BOC Sciences  
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Products Intro: Product Name:H-1152 Glycyl Dihydrochloride
CAS:913844-45-8
H-1152Glycyl, Dihydrochloride Basic information
Product Name:H-1152Glycyl, Dihydrochloride
Synonyms:(2S)-4-(Aminoacetyl)hexahydro -2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride;2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride;H-1152Glycyl, Dihydrochloride;(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl) sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride;(S)-Glycyl-H-1152 (hydrochloride);Glycyl-H 1152 2HCl
CAS:913844-45-8
MF:C18H26Cl2N4O3S
MW:0
EINECS:
Product Categories:All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Protein Kinase
Mol File:913844-45-8.mol
H-1152Glycyl, Dihydrochloride Structure
H-1152Glycyl, Dihydrochloride Chemical Properties
mp 190-192°C
storage temp. Refrigerator
Stability:Hygroscopic
Safety Information
MSDS Information
H-1152Glycyl, Dihydrochloride Usage And Synthesis
Chemical PropertiesPale-Yellow Solid
UsageA glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.
Biological ActivityGlycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride ((S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride ) that displays improved ROCKII selectivity. IC 50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μ M for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.
H-1152Glycyl, Dihydrochloride Preparation Products And Raw materials
Tag:H-1152Glycyl, Dihydrochloride(913844-45-8) Related Product Information
H-1152Glycyl, Dihydrochloride FASUDIL (S)-(+)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLYNYL)SULFONYL]HOMOPIPERAZINE