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Mycophenolic acid

CAS No.24280-93-1
Chemical Name:Mycophenolic acid
Synonyms:68618;melbex;nsc-129185;lilly-68618;Mycophenolic;Mycophenolinsure;micofenolicoacido;MYCOPHENOLIC ACID;Micophenolic acid;MYCOPHENOLIC ACID 98%
CBNumber:CB8311003
Molecular Formula:C17H20O6
Formula Weight:320.34
MOL File:24280-93-1.mol
Mycophenolic acid Property
mp : 141°C
storage temp. : 2-8°C
solubility : methanol: 50 mg/mL, clear, colorless to faintly yellow
form : powder
Merck : 13,6352
CAS DataBase Reference: 24280-93-1(CAS DataBase Reference)
Safety
Hazard Codes : Xn,N,T,F
Risk Statements : 22-61-40-68-50/53-48/25-52/53-36-20/21/22-11
Safety Statements : 53-45-36/37-61-22-26-16
RIDADR : 2811
WGK Germany : 3
RTECS : MP8050000
F : 10
HazardClass : 6.1(b)
PackingGroup : III

Mycophenolic acid Chemical Properties,Usage,Production

Chemical Properties
White to Off-White Powder
Usage
An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
Usage
immune suppressant, antineoplastic, antiviral
Usage
antineoplastic, progestin
Usage
Mycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation showed mycophenolic acid to display broad antitumour, antiviral, antifungal and antiprotozoan activities. Its potent immunosuppressant activity led to its commercial development to prevent kidney transplant rejection. Mycophenolic acid acts by inhibiting inosine monophosphate dehydrogenase, controlling the rate of de novo purine synthesis in proliferating B and T lymphocytes.
Usage
Mycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation showed mycophenolic acid to display broad antitumor, antiviral, antifungal and antiprotozoan activities. Its potent immunosuppressant activity led to its commercial development to prevent kidney transplant rejection. Mycophenolic acid acts by inhibiting inosine monophosphate dehydrogenase, controlling the rate of de novo purine synthesis in proliferating B and T lymphocytes.
Biological Activity
Immunosuppressive agent with antiviral and antitumor effects in vitro and in vivo . Potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. Reversibly inhibits proliferation of T and B lymphocytes and antibody formation.
Mycophenolic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Mycophenolic acid Suppliers      Global( 194)Suppliers     
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Zheda Panaco Chemical Engineering Co., Ltd +86-571-86770761/87986637+86-571-87984136panaco@zhedachem.com,panaco@mail.hz.zj.cnCHINA 98 60
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921；+86-10-82826195+86-10-82826195sales@pharmacodia.comCHINA 283 55
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)sh@meryer.comCHINA 40407 62
INTATRADE GmbH +49 3493/605464+49 3493/605470sales@intatrade.deGERMANY 3590 66
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Chembest Research Laboratories Limited +86(0)21-20908456+86(0)21-58180499sales@biochembest.comCHINA 6000 61
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TCI (Shanghai) Development Co., Ltd. ----info@chemicalbook.comCHINA 22159 81
Beijing Ouhe Technology Co., Ltd +86-10-4006331231;+86-10-51280831;+86-10-82967028+86-10-82967029sales@ouhechem.comCHINA 10815 60
 
24280-93-1(Mycophenolic acid)Related Search:
Thiophanate-methyl Citric acid ACETIC ACID Salvianolic acid B Anisole Folic acid Stearic acid Methoxy (Trifluoromethoxy)benzene Mycophenolate mofetil Anisic aldehyde Mycophenolic acid CHLOROPHOSPHONAZO III Bensulfuron methyl Salvianolic acid Mycophenolate mofetil Methyl acrylate ASCORBICACID
4-methyl-5-methoxy-7-hydroxy-6-(5-carboxy-3-methylpent-2-en-1-yl)-phthalide 6-(5-carboxy-3-methyl-2-pentenyl)-7-hydroxy-5-methoxy-4-methyl-phthalid lilly-68618 melbex micofenolicoacido nsc-129185 (4E)-6-(1,3-DIHYDRO-4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-5-ISOBENZOFURANYL)-4-METHYL-4-HEXENOIC ACID 6-(4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-5-PHTHALANYL)-4-METHYL-4-HEXANOIC ACID 6-[4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-5-PHTHALANYL]-4-METHYL-4-HEXENOIC ACID 6-(1,3-DIHYDRO-4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-5-ISOBENZOFURANYL)-4-METHYL-4-HEXENOIC ACID 6-(1,3-DIHYDRO-7-HYDROXY-5-METHOXY-4-METHYL-1-OXOISOBENZOFURAN-6-YL)-4-METHYL-4-HEXANOIC ACID 24280-93-1 Antibiotics Antibiotics G-M Antibiotics A to Z BioChemical MYCOPHENOLIC ACID mycophenolic acid from penicillium brevi-compactum mycophenolic acid from penicillium*brevi-compactu MYCOPHENOLIC ACID 98% 24280-91-1 Mycophenolic 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- Mycophenolinsure Active Pharmaceutical Ingredients Aromatics Compounds Aromatics Inhibitors Intermediates & Fine Chemicals Pharmaceuticals 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid, 6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid C17H17O6D3 (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid 68618 Micophenolic acid Mycophenolic acid,6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid, 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid Mycophenolic acid/(E)-6-(4-hydroxy-6-Methoxy-7-Methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-Methylhex-4-enoic acid (4Z)-6-(4-hydroxy-6-Methoxy-7-Methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-Methylhex-4-enoic acid Mycophenolic acid(Mycophenolate) (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid (E)-6-(4-hydroxy-6-Methoxy-7-Methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-Methylhex-4-enoic acid Mycophenolic acid (MPA) Related Substance Isotopically Labeled Pharmaceutical Reference Standard antibiotic Melbex, Lilly 68618, NSC 129185 Mycophenolic acid SynonyMs 6-(1,3-Dihydro-7-hydroxy-5-Methoxy-4-Methyl-1-oxoisobenzofuran-6-yl)-4-Methyl-4-hexanoic acid Mycophenolic acid 6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid Mycophenolic acid solution
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