Mycophenolic acid

Mycophenolic acid Suppliers list
Company Name:Zheda Panaco Chemical Engineering Co., Ltd  Gold
Tel:+86-571-86770761/87986637
Email:panaco@zhedachem.com,panaco@mail.hz.zj.cn
Products Intro: Product Name:Mycophenolic acid
CAS:24280-93-1
Purity:98% Package:25kg
Company Name:Pharmacodia (Beijing) Co.,Ltd  Gold
Tel:+86-400-851-9921;+86-10-82826195
Email:sales@pharmacodia.com
Products Intro: Product Name:Mycophenolic acid
CAS:24280-93-1
Purity:0.99 Package:299RMB/100mg; 699RMB/1g
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:Mycophenolic acid
CAS:24280-93-1
Purity:98% Package:1G,250Mg
Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel:+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)
Email:sh@meryer.com
Products Intro: Product Name:Mycophenolic Acid
CAS:24280-93-1
Purity:>98.0%(LC)(T) Package:1g;5g Remarks:M2216
Company Name:INTATRADE GmbH  
Tel:+49 3493/605464
Email:sales@intatrade.de
Products Intro: Product Name:Mycophenolic acid Synonyms 6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid
CAS:24280-93-1
Remarks:PS02409
Mycophenolic acid Basic information
Product Name:Mycophenolic acid
Synonyms:4-methyl-5-methoxy-7-hydroxy-6-(5-carboxy-3-methylpent-2-en-1-yl)-phthalide;6-(5-carboxy-3-methyl-2-pentenyl)-7-hydroxy-5-methoxy-4-methyl-phthalid;lilly-68618;melbex;micofenolicoacido;nsc-129185;(4E)-6-(1,3-DIHYDRO-4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-5-ISOBENZOFURANYL)-4-METHYL-4-HEXENOIC ACID;6-(4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-5-PHTHALANYL)-4-METHYL-4-HEXANOIC ACID
CAS:24280-93-1
MF:C17H20O6
MW:320.34
EINECS:246-119-3
Product Categories:Active Pharmaceutical Ingredients;Aromatics Compounds;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Related Substance;Isotopically Labeled Pharmaceutical Reference Standard;antibiotic
Mol File:24280-93-1.mol
Mycophenolic acid Structure
Mycophenolic acid Chemical Properties
mp 141°C
storage temp. 2-8°C
solubility methanol: 50 mg/mL, clear, colorless to faintly yellow
form powder
Merck 13,6352
CAS DataBase Reference24280-93-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,N,T,F
Risk Statements 22-61-40-68-50/53-48/25-52/53-36-20/21/22-11
Safety Statements 53-45-36/37-61-22-26-16
RIDADR 2811
WGK Germany 3
RTECS MP8050000
10
HazardClass 6.1(b)
PackingGroup III
MSDS Information
ProviderLanguage
Mycophenolic acid English
SigmaAldrich English
Mycophenolic acid Usage And Synthesis
Chemical PropertiesWhite to Off-White Powder
UsageAn antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
Usageimmune suppressant, antineoplastic, antiviral
Usageantineoplastic, progestin
UsageMycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation showed mycophenolic acid to display broad antitumour, antiviral, antifungal and antiprotozoan activities. Its potent immunosuppressant activity led to its commercial development to prevent kidney transplant rejection. Mycophenolic acid acts by inhibiting inosine monophosphate dehydrogenase, controlling the rate of de novo purine synthesis in proliferating B and T lymphocytes.
UsageMycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation showed mycophenolic acid to display broad antitumor, antiviral, antifungal and antiprotozoan activities. Its potent immunosuppressant activity led to its commercial development to prevent kidney transplant rejection. Mycophenolic acid acts by inhibiting inosine monophosphate dehydrogenase, controlling the rate of de novo purine synthesis in proliferating B and T lymphocytes.
Biological ActivityImmunosuppressive agent with antiviral and antitumor effects in vitro and in vivo . Potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. Reversibly inhibits proliferation of T and B lymphocytes and antibody formation.
Mycophenolic acid Preparation Products And Raw materials
Tag:Mycophenolic acid(24280-93-1) Related Product Information
Thiophanate-methyl Citric acid ACETIC ACID Salvianolic acid B Anisole Folic acid Stearic acid Methoxy (Trifluoromethoxy)benzene Mycophenolate mofetil Anisic aldehyde Mycophenolic acid CHLOROPHOSPHONAZO III Bensulfuron methyl Salvianolic acid Mycophenolate mofetil Methyl acrylate ASCORBICACID