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| CAS No. | 857876-30-3 |
| Chemical Name: | AMG-706 |
| Synonyms: | AMG-706;Unii-T6Q3060U91;Diphosphate salt;Motesanib(AMG-706);Motesanib diphosphate;Motesanib, Diphosphate Salt;Motesanib diphosphate [usan];Motesanib Diphosphate (AMG-706);N-(2,3-Dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-3-pyridinecarboxaMide Phosphate;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide diphosphate |
| CBNumber: | CB12473858 |
| Molecular Formula: | C22H23N5O |
| Formula Weight: | 0 |
| MOL File: | Mol file |
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AMG-706 Chemical Properties,Usage,Production |
Usage
An oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma. |
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Usage
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively. |
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| AMG-706 Preparation Products And Raw materials |
Raw materials
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Preparation Products
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| AMG-706 Suppliers Global( 35)Suppliers |
| Supplier | Tel | Fax | Email | Country | ProdList | Advantage |
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Shanghai Boyle Chemical Co., Ltd.
| Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market) | 86-21-57758967 | sales@boylechem.com | CHINA |
5604
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55
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Chembest Research Laboratories Limited
| +86(0)21-20908456 | +86(0)21-58180499 | sales@biochembest.com | CHINA |
6000
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61
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Chemsky (shanghai) International Co.,Ltd
| 021-50135380 | | shchemsky@sina.com | CHINA |
15730
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60
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Jinan Trio PharmaTech Co., Ltd.
| +86 (531) 88811793；+86 (531) 88811783;+(0)18854807083; | +86 (531) 55696010 QQ981200479 | sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market) | CHINA |
1779
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62
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Wuhan TCASChem Technology Co., Ltd.
| +86-027-51830495,13035119173,13986148687 | +86-027-86697669，QQ:695274159;947257336 | sales@tcaschem.com | CHINA |
3820
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55
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NCE Biomedical Co.,Ltd.
| 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988 | +86-27-87599188 | sales@ncebiomed.com | CHINA |
1503
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55
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Shanghai Haoyuan Chemexpress Co., Ltd
| 86-21-58998590 | 86-21-53700326, 86-21-58998590 | sales@chemexpress.cn | CHINA |
10011
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61
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
| 021-20337333/400-620-6333 | 021-50323701 | sale@aladdin-e.com | CHINA |
24330
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65
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MedChemexpress LLC
| 609-228-6898 | 609-228-5909 | sales@medchemexpress.cn | USA |
4935
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58
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AdooQ BioScience, LLC
| +1 (866) 930-6790 | +1 (866) 333-9607 | info@adooq.com | USA |
2786
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58
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857876-30-3
AMG-706
Motesanib(AMG-706)
Motesanib diphosphate
Motesanib diphosphate [usan]
Unii-T6Q3060U91
N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide diphosphate
C22H23N5O2H3PO4
Aromatics
Heterocycles
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals
C22H29N5O9P2
Motesanib, Diphosphate Salt
N-(2,3-Dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-3-pyridinecarboxaMide Phosphate
Motesanib Diphosphate (AMG-706)
Antineoplastic
Diphosphate salt
3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-, phosphate (1:2)
57876-30-3
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