AMG-706

Company Name:	Shanghai Boyle Chemical Co., Ltd.
Tel:	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)
Email:	sales@boylechem.com
Products Intro:	Product Name:AMG-706 CAS:857876-30-3

Company Name:	Chembest Research Laboratories Limited
Tel:	+86(0)21-20908456
Email:	sales@biochembest.com
Products Intro:	Product Name:Motesanib diphosphate salt CAS:857876-30-3 Remarks:C13908

Company Name:	Chemsky (shanghai) International Co.,Ltd
Tel:	021-50135380
Email:	shchemsky@sina.com
Products Intro:	Product Name:Motesanib, Diphosphate Salt CAS:857876-30-3 Purity:99+% Package:5Mg;25Mg;50Mg;100Mg;250Mg;500Mg

Company Name:	Jinan Trio PharmaTech Co., Ltd.
Tel:	+86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;
Email:	sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)
Products Intro:	Product Name:Motesanib Diphosphate (AMG-706) CAS:857876-30-3 Purity:99% Package:5Mg, 10Mg, 20Mg, 50Mg

Company Name:	Wuhan TCASChem Technology Co., Ltd.
Tel:	+86-027-51830495,13035119173,13986148687
Email:	sales@tcaschem.com
Products Intro:	Product Name:N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide CAS:857876-30-3 Purity:95% HPLC Package:5g,10g,25g,100g,1kg

AMG-706 Basic information

Product Name:	AMG-706
Synonyms:	AMG-706;Motesanib(AMG-706);Motesanib diphosphate;Motesanib diphosphate [usan];Unii-T6Q3060U91;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide diphosphate;Motesanib, Diphosphate Salt;N-(2,3-Dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-3-pyridinecarboxaMide Phosphate
CAS:	857876-30-3
MF:	C22H23N5O
MW:	0
EINECS:
Product Categories:	Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Antineoplastic
Mol File:	Mol File

AMG-706 Chemical Properties

Safety Information

MSDS Information

AMG-706 Usage And Synthesis

Usage	An oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.
Usage	Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.

AMG-706 Preparation Products And Raw materials

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