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Indometacin
Indometacin Suppliers list
Company Name:
BEST-REAGENT
Gold
Tel:
028-85973071 028-85973075
Email:
service@best-reagent.com
Products Intro:
Product Name:IndoMethacin
CAS:53-86-1
Purity:99% Package:5g,25g,100,500g,1Kg
Company Name:
Wuhan Hezhong Bio-chemical Manufacture co ltd
Gold
Tel:
021-68580270 / 18121115343
Email:
foodinfo@yccreate.com
Products Intro:
Product Name:Indometacin
CAS:53-86-1
Purity:99% HPLC Package:100G;500G;1KG;25KG
Company Name:
WuHan YuanCheng Gongchuang Technology Co.Ltd
Gold
Tel:
027-50756129/250/126/076
Email:
gy08@yccreate.com
Products Intro:
Product Name:Indometacin
CAS:53-86-1
Purity:99% Package:25kg/carton
Company Name:
J & K SCIENTIFIC LTD.
Tel:
400-666-7788 +86-10-82848833
Email:
jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro:
Product Name:IndoMethacin
CAS:53-86-1
Purity:98.0%(LC&T) Package:25G,500G
Company Name:
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:
+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)
Email:
sh@meryer.com
Products Intro:
Product Name:IndoMethacin
CAS:53-86-1
Purity:>98.0%(LC)(T) Package:25g;500g Remarks:I0655
Indometacin Basic information
Product Name:
Indometacin
Synonyms:
AURORA KA-6542
;
INDOCIN
;
INDOMETACIN
;
INDOMETACINE
;
INDOMETHACIN
;
INDOMETHACINE
;
LABOTEST-BB LT00244830
;
1-(P-CHLOROBENZYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID
CAS:
53-86-1
MF:
C19H16ClNO4
MW:
357.79
EINECS:
200-186-5
Product Categories:
PHARMACEUTICALS
;
Active Pharmaceutical Ingredients
;
All Inhibitors
;
Inhibitors
;
Intermediates & Fine Chemicals
;
Lipid signaling
;
INDOCIN
;
Other APIs
;
Pharmaceutical raw chemicals
Mol File:
53-86-1.mol
Indometacin Chemical Properties
mp
155-162 °C
storage temp.
Store at RT
solubility
ethanol: 50 mg/mL, clear, yellow-green
Merck
4968
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
53-86-1(CAS DataBase Reference)
NIST Chemistry Reference
Indomethacin(53-86-1)
EPA Substance Registry System
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy- 2-methyl-(53-86-1)
Safety Information
Hazard Codes
T+,Xi,T
Risk Statements
28-36/37/38-39/23/24/25-23/24/25
Safety Statements
28-36/37-45-36-26
RIDADR
UN 2811 6.1/PG 1
WGK Germany
3
RTECS
NL3500000
F
8-10
HazardClass
6.1
PackingGroup
I
Hazardous Substances Data
53-86-1(Hazardous Substances Data)
MSDS Information
Provider
Language
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
English
SigmaAldrich
English
ALFA
English
Indometacin Usage And Synthesis
Chemical Properties
Crystalline Solid
Usage
Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD
Usage
antiinflammatory, antipyretic, analgesic
General Description
Crystals.
Air & Water Reactions
Practically insoluble in water. Decomposes in alkali.
Reactivity Profile
A weak organic acid.
Fire Hazard
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Biological Activity
Cyclooxgenase (COX) inhibitor; displays selectivity for COX-1 (IC 50 values are 230 and 630 nM for human COX-1 and COX-2 respectively). Widely used anti-inflammatory agent.
Indometacin Preparation Products And Raw materials
Preparation Products
Acemetacin
-->
indomethacin farnesil
Raw materials
p-Anisidine
-->
Levulinic acid
-->
4-Chlorobenzoyl chloride
Tag:
Indometacin(53-86-1)
Related Product Information
Diclofenac potassium
Talmetacin
AURORA KA-4884
INDOMETHACIN SODIUM
TROPESIN
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(2 -((4-(benzoylamino)-5-(dipropylamino)-1,5-dioxopentyl)oxy)ethoxy)-2-ox oethyl ester, (+-)-
(4-Fluorophenyl)methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol e-3-acetate
2-carboxyphenyl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetate
PROGLUMETACIN MALEATE
2-((2-carboxyphenoxy)carbonyl)phenyl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetate
Acemetacin
Indometacin
4-Chlorophenylacetic acid
Methoxyacetic acid
Indole
Methyl acrylate
4-Methoxyphenylacetic acid
ACETIC ACID
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