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CAS-Nr. | 50-02-2 |
Bezeichnung: | Dexamethason |
Englisch Name: | Dexamethasone |
Synonyma: | Dexamethason DXM;Dexa;Dxms;mk125;Corson;Dexone;Dezone;Hl-dex;MK 125;Auxiron |
CBNumber: | CB4261243 |
Summenformel: | C22H29FO5 |
Molgewicht: | 392.46 |
MOL-Datei: | 50-02-2.mol |
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Dexamethason physikalisch-chemischer Eigenschaften |
Schmelzpunkt:: |
262-264 °C(lit.)
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alpha : |
75 º (c=1, dioxane) |
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Brechungsindex: |
76 ° (C=1, Dioxane) |
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solubility : |
ethanol: 1 mg/mL
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Wasserlöslichkeit: |
10 mg/100 mL (25 ºC) |
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Stabilität:: |
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive. |
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Dexamethason Chemische Eigenschaften,Einsatz,Produktion Methoden |
Chemische Eigenschaften White Crystalline Solid |
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Verwenden A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase |
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Verwenden Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthas
e. |
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Allgemeine Beschreibung Odorless white to off-white crystalline powder with a slightly bitter taste. |
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Air & Water Reaktionen Insoluble in water. |
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Reaktivität anzeigen Dexamethasone may be sensitive to prolonged exposure to light. Dexamethasone is incompatible with strong oxidizers, strong acids, acid chlorides and acid anhydrides. Oxidation may occur with bases. |
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Brandgefahr Flash point data for Dexamethasone are not available; however, Dexamethasone is probably combustible. |
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R-Sätze Betriebsanweisung: R43:Sensibilisierung durch Hautkontakt möglich. R40:Verdacht auf krebserzeugende Wirkung. R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut. R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut. |
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S-Sätze Betriebsanweisung: S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen. S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen). S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen. S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren. S22:Staub nicht einatmen. |
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Biologische Aktivit?t Glucocorticoid; anti-inflammatory. Reduces levels of activated NF- κ B in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. |
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Dexamethason Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
Beclometason
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Dexamethason Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 184)Lieferanten |
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Complex Molecules
Immune Cell Signaling and Blood
Immune System Regulation
Immunomodulators and Antibiotics
16alpha)-
16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-(11bet
16alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-2,20-dione
16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,2
16-alpha-Methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione
16-alpha-methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-dien
16alpha-Methyl-9alpha-fluoro-11beta-17alpha-21-trihydroxypregna-1,4-diene-3,20-dione
16-alpha-methyl-9-alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16-alpha-methyl-9-alpha-fluoro-delta(sup1)-hydrocortisone
16alpha-Methyl-9alpha-fluoro-delta(sup1)-hydrocortisone
16alpha-methyl-9alpha-fluoro-delta1-hydrocortisone
16-alpha-methyl-9-alpha-fluoroprednisolone
16alpha-Methyl-9alpha-fluoroprednisolone
17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-diene-9-alpha-fluoro-11-bet
17-alpha,21-triol-3,20-9-alpha-fluoro-16-alpha-methyl-4-pregnadiene-11-beta
1-dehydro-16alpha-methyl-0alpha-fluorohydrocortisone
1-dehydro-16-alpha-methyl-9-alpha-fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
3,20-dione.
4-alpha-fluoro-16-alpha-methyl-11-beta,17,21-trihydroxypregna-1,4-diene-3,20
4-alpha-fluoro-16-alpha-methyl-11-beta,17,21-trihydroxypregna-1,4-diene-3,20-d
4alpha-Fluoro-16alpha-methyl-11beta-17,21-trihydroxypregna-1,4-diene-3,20-dione
4-diene-3,20-dione,9-fluoro-11,17,21-trihydroxy-16-methyl-,(11.beta.,16.alpha.)-Pregna-1
6alpha)-
9-alpha-fluoro-11-beta,17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-dien
9alpha-Fluoro-11beta-17alpha- 21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
9-alpha-fluoro-16-alpha-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,2
9alpha-Fluoro-16alpha-methyl-1,4-pregnadiene-11beta-17-alpha-21-triol-3,20-dione
9alpha-Fluoro-16alpha-methyl-11beta,17alpha,21beta-trihydroxy-pregna-1,4-diene-3,20-dione
Aeroseb-D
Aeroseb-Dex
anaflogistico
Aphtasolon
Auxiron
Bisu DS
component of Azimycin
component of Azium
component of Deronil
component of Dronactin
Corson
Corsone
Cortisumman
Decaderm
Decadron Tablets, Elixir
decalix
Decaspray
Dekacort
delta(sup1)-9-alpha-fluoro-16-alpha-methylcortisol
delta1-9-alpha-Fluoro-16-alpha-methylcortisol
Deltafluorene
Dergramin
Desadrene
Desametasone
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