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CONCANAMYCIN A

CONCANAMYCIN A Suppliers list
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:Concanamycin A, Streptomyces sp.
CAS:80890-47-7
Purity:>90% Package:0.1mg, 1mg
Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel:86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email:67055399@qq.com
Products Intro: Product Name:ConcanaMycin A;(3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(AMinocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-Methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-Methylbutyl]-9-ethyl-8,10-
CAS:80890-47-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name:Dalian Meilun Biotech Co., Ltd.  
Tel:0411-66771943；0411-66771942
Email:sales@meilune.com
Products Intro: Product Name:ConcanaMycin A
CAS:80890-47-7
Purity:> 95%,BR Package:100 μg
Company Name:ShangHai YuanYe Biotechnology Co., Ltd.  
Tel:021-61312847 qq：2797782341
Email:2797782341@qq.com
Products Intro: Product Name:ConcanaMycin A
CAS:80890-47-7
Purity:BR,99% Package:25ug
Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD  
Tel:021-20337333/400-620-6333
Email:sale@aladdin-e.com
Products Intro: Product Name:ConcanaMycin A
CAS:80890-47-7
Purity:80% Package:25UG,100UG
CONCANAMYCIN A Basic information
Product Name:CONCANAMYCIN A
Synonyms:antibioticx4357b;x4357b;FOLIMYCIN;FOLIMYCIN, STREPTOMYCES SP;FOLIMYCIN, STREPTOMYCES SPECIES;CONCANAMYCIN A;CONCANAMYCIN A, STREPTOMYCES SP;concanamycin A from streptomyces species
CAS:80890-47-7
MF:C46H75NO14
MW:866.09
EINECS:
Product Categories:
Mol File:80890-47-7.mol
CONCANAMYCIN A Structure
CONCANAMYCIN A Chemical Properties
mp 179-180℃ (dichloromethane ethanol )
storage temp. −20°C
Safety Information
Hazard Codes T+
Risk Statements 26/27/28-36
Safety Statements 26-36/37/39-45
RIDADR UN 3462 6.1/PG 2
WGK Germany 3
RTECS CB9732000
F 10-21
HazardClass 6.1(b)
PackingGroup III
MSDS Information
ProviderLanguage
SigmaAldrich English
CONCANAMYCIN A Usage And Synthesis
UsageConcanamycin A is the major analogue of the concanamycin complex produced by Streptomyces sp.. It has been shown to act as a potent and specific vacuolar-ATPase inhibitor. Concanamycin A inhibits the acidification of organelles and blocks cell surface expression of viral envelope glycoproteins without affecting their synthesis. It also interferes with intracellular protein trafficking and inhibits perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity. Concanamycins are structurally related to the bafilomycins.
Biological ActivitySpecific inhibitor of V-type (vacuolar) H + -ATPase that displays > 2000-fold selectivity over other H + -ATPases (IC 50 values are 9.2, > 20000, > 20000 and > 20000 nM for yeast V-type, F-type, P-type H + -ATPases and porcine P-type Na + ,K + -ATPase respectively). Blocks cell surface expression of virus envelope glycoproteins without affecting synthesis and exhibits cytotoxicity in several cell lines.
CONCANAMYCIN A Preparation Products And Raw materials
Tag:CONCANAMYCIN A(80890-47-7) Related Product Information
concanamycin G concanamycin E concanamycin D BUTYL SORBATE hedonal 2-ethoxyethyl carbamate viranamycin B 2,4-DECADIEN-1-OL Ethyl-2,4-decadienoate trans,trans-2,4-undecadienal 2-methoxyethyl carbamate (E,E)-2,4-Dodecadienal CONCANAMYCIN A 2,4-DECADIENOIC ACID METHYL ESTER ISODECYL ACRYLATE 2,4-UNDECADIEN-1-OL HYDROXYPROPYLCARBAMATE 2,4-NONADIEN-1-OL