Company Name: | Chemvon Biotechnology Co., Ltd Gold |
Tel: | +86-21-50790412 |
Email: | marketing@chemvon.com |
Products Intro: |
Product Name:Aprepitant CAS:170729-80-3 Purity:98% Package:1g, 10g, 100g, 200g, 1kg, 5kg |
Company Name: | Enantiotech Corporation Ltd Gold |
Tel: | 0086-760-85282375 |
Email: | marketing01@enantiotech.net |
Products Intro: |
Product Name:Aprepitant; 5-[2(R)-[1(R)-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)Morpholin-4-ylMethyl]-3,4-dihydro-2H-1,2,4-triazol-3-one CAS:170729-80-3 Purity:≧98.5% Package:25KG 10KG 5KG 1KG |
Company Name: | Shanghai Biosundrug Co., Ltd Gold |
Tel: | 86-21-34622192-/-86-021-34622765 |
Email: | shxiaocai@hotmail.com |
Products Intro: |
Product Name:Aprepitant CAS:170729-80-3 Purity:99% HPLC Package:1KG,5KG;10KG;25KG |
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| Aprepitant Basic information |
Product Name: | Aprepitant | Synonyms: | 5-[2(r)-[1(r)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(s)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2h-1,2,4-triazol-3-one;aprepitant;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one, Emend;5-[2(R)-[1(R)-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2H-1,2,4-triazol-3-one;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;Emend;MK-0869 | CAS: | 170729-80-3 | MF: | C23H21F7N4O3 | MW: | 534.4266624 | EINECS: | | Product Categories: | Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Aprepitant | Mol File: | 170729-80-3.mol | |
| Aprepitant Chemical Properties |
| Aprepitant Usage And Synthesis |
Chemical Properties | Off-White to Light Yellow Cyrstalline Solid | Usage | A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and
CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. | Usage | anticholinergic |
| Aprepitant Preparation Products And Raw materials |
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