CALPAIN INHIBITOR I

Company Name:	J & K SCIENTIFIC LTD.
Tel:	400-666-7788 +86-10-82848833
Email:	jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro:	Product Name:Calpain Inhibitor I CAS:110044-82-1 Purity:>98% Package:10mg, 50mg

Company Name:	Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:	+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)
Email:	sh@meryer.com
Products Intro:	Product Name:Calpain Inhibitor I CAS:110044-82-1 Purity:96% Remarks:32815

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email:	67055399@qq.com
Products Intro:	Product Name:MG 101;N-Acetyl-L-leucine-L-leucine-L-norleucinal CAS:110044-82-1 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g

Company Name:	Alabiochem Tech.Co., Ltd.
Tel:	0086-512-58900862; 400-0707-518; 0086-512-56727736
Email:	sales@alabiochem.com
Products Intro:	Product Name:Calpain Inhibitor I CAS:110044-82-1 Purity:>98% Package:250Mg, 500Mg,1g,5g

Company Name:	Shanghai Hanhong Chemical Co., Ltd.
Tel:	021-61521197,021-60496702,021-54302127,021-54306202,021-61525701,021-54308259
Email:	jerry.ma@hanhonggroup.com
Products Intro:	Product Name:Calpain Inhibitor I CAS:110044-82-1 Remarks:9P02

CALPAIN INHIBITOR I Basic information

Product Name:	CALPAIN INHIBITOR I
Synonyms:	acetylleucyl-leucyl-norleucinal;N-AC-LEU-LEU-NORLEUCINAL;N-ACETYL-LEU-LEU-NLE-CHO;N-ACETYL-L-LEUCYL-L-LEUCYL-L-NORLEUCINAL;N-ACETYL-LEU-LEU-NORLEUCINAL;MG 101;LLNL;CALPAIN INHIBITOR
CAS:	110044-82-1
MF:	C20H37N3O4
MW:	383.53
EINECS:
Product Categories:	Calpain I;Calpain I Inhibitors;Cathepsin L;Lysosomal Proteases;Nitric Ox;A to C;Aldehydes;and Substrates;Apoptosis Enzymes;Application Index;Bioactive Small Molecules;Biochemicals and Reagents;Building Blocks;C13-C60;Calpain;Calpain and Proteasome Inhibitors;Calpain II;Calpain II Inhibitors;Carbonyl Compounds;Cathepsin B;Cathepsin/Granzyme Inhibitors &;C-CH;Cell Biology;Cell Signaling and Neuroscience;Cell Signaling Enzymes;Chemical Synthesis;Endoplasmic Reticulum Stress;Enzyme Inhibitors;Enzyme Inhibitors by Enzyme;Enzymes;Inhibitors;Intracellular Protein Degradation;Substrates;ProteasomeInhibitors;inhibitor;peptides
Mol File:	110044-82-1.mol

CALPAIN INHIBITOR I Chemical Properties

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

CALPAIN INHIBITOR I Usage And Synthesis

Chemical Properties	white to off-white powder
Usage	Calpain inhibitor I reversibly blocks the calcium-dependent neutral cysteine protease calpain I. Calpains have been implicated in various cellular processes, including cell proliferation, apoptosis, and cell differentiation.
Biological Activity	Calpain inhibitor (IC 50 = 0.09 μ M) that activates p53-dependent apoptosis in tumor cell lines. Increases activated p53, p21 and caspase levels and promotes cell cycle arrest through inhibition of cyclin D degradation in vitro . Also attenuates ischemia/reperfusion injury in cardiomyocytes, hepatocytes and renal tubular cells through downregulation of iNOS and COX-2 expression.

CALPAIN INHIBITOR I Preparation Products And Raw materials

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