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7-Ethyl-10-hydroxycamptothecin

7-Ethyl-10-hydroxycamptothecin Suppliers list
Company Name:SiChuang NanBu Honesty Technology Co., Ltd.  Gold
Tel:0838-5675166
Email:nbcxkj@126.com
Products Intro: Product Name:7-Ethyl-10-hydroxycamptothecin
CAS:86639-52-3
Company Name:Tianyuan Natural Product Co.,Ltd.  Gold
Tel:86-28-85012281 13808177790
Email:xianlihong8888@163.com
Products Intro: Product Name:7–Ethyl–10–hydroxycamptothecin
CAS:86639-52-3
Purity:99% HPLC Package:1KG;2KG;5KG
Company Name:Shanghai Biocompounds Chemlab  Gold
Tel:+86-21-57687675-882/885/886
Email:yanjie@biocompounds.com
Products Intro: Product Name:7-Ethyl-10-HydroxycaMptothecin
CAS:86639-52-3
Purity:99.5% Package:1KG,25KG,100KG
Company Name:Shanghai Boyle Chemical Co., Ltd.  
Tel:Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)
Email:sales@boylechem.com
Products Intro: Product Name:7-Ethyl-10-hydroxycamptothecin
CAS:86639-52-3
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:7-Ethyl-10-hydroxycaMptothecin
CAS:86639-52-3
Purity:99% Package:100MG,500MG
7-Ethyl-10-hydroxycamptothecin Basic information
Product Name:7-Ethyl-10-hydroxycamptothecin
Synonyms:CAMPTOTHECIN, 7-ETHYL-10-HYDROXY;4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;7-ETHYL-10-HYDROXYCAMPTOTHECIN;7-ETHYL-10-HYDROXYCAMPTOTHECINE;7-ETHYL-10-HYDROXY-CPT;SN38;10-dihydroxy-;4’:6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione,4,7-diethyl-1h-pyrano(3
CAS:86639-52-3
MF:C22H20N2O5
MW:392.4
EINECS:
Product Categories:Pharmaceutical Raw Materials;Miscellaneous Natural Products;Antitumors for Research and Experimental Use;Biochemistry;Natural Plant Extract;Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Natural Anti-cancer Medical Materials and It's Derivatives;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:86639-52-3.mol
7-Ethyl-10-hydroxycamptothecin Structure
7-Ethyl-10-hydroxycamptothecin Chemical Properties
mp 217 °C
refractive index 21.5 ° (C=0.2, THF)
storage temp. −20°C
CAS DataBase Reference86639-52-3(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
RTECS UQ0491000
MSDS Information
7-Ethyl-10-hydroxycamptothecin Usage And Synthesis
Chemical PropertiesLight-Yellow Solid
UsageA metabolite of Irinotecan, a DNA topoisomerase inhibitor
Biological ActivityActive metabolite of CPT-11 that inhibits DNA topoisomerase I (IC 50 values are 0.74 and 1.9 μ M in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC 50 values are 0.077 and 1.3 μ M respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC 50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).
7-Ethyl-10-hydroxycamptothecin Preparation Products And Raw materials
Preparation ProductsIrinotecan
Tag:7-Ethyl-10-hydroxycamptothecin(86639-52-3) Related Product Information
7-ETHYL-10-HYDROXYCAMPTOTHECIN,98% (4R)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione 7-ethyl-10-hydroxycamptothecin beta-glucuronide Hydroxyl camptothecine Ethyl vanillin 1-Hydroxyethylidene-1,1-diphosphonic acid (+)-Camptothecin Diethyl ether Ethylenzene Etanol 7-Ethyl-10-hydroxycamptothecin Ethyl propionate Camptothecin Series--10-hydroxycamptothecin Ethyl acetate Ethyl formate Ethyl acrylate Ethylparaben 10-HYDROXYCAMPTOTHECIN