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AG 490

AG 490 Suppliers list
Company Name:NCE Biomedical Co.,Ltd.  Gold
Tel:4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988
Email:sales@ncebiomed.com
Products Intro: Product Name:AG-490
CAS:133550-30-8
Purity:99% HPLC Package:50Mg,100Mg,500Mg,1g,5g,10g,50g,100g,500g,1kg Remarks:XYA0003
Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel:86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email:67055399@qq.com
Products Intro: Product Name:AG 490;(E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylMethyl)-2-propenaMide
CAS:133550-30-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name:Chembest Research Laboratories Limited  
Tel:+86(0)21-20908456
Email:sales@biochembest.com
Products Intro: Product Name:AG 490(Tyrphostin AG 490,Tyrphostin B42)
CAS:133550-30-8
Remarks:C13261
Company Name:VDM Biochemicals   
Tel:0330-2528181
Email:sales@vdmbio.com
Products Intro: Product Name:AG 490
CAS:133550-30-8
Purity:>=98% by HPLC Package:60USD/10mg
Company Name:Jinan Trio PharmaTech Co., Ltd.  
Tel:+86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;
Email:sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)
Products Intro: Product Name:AG-490 (Tyrphostin B42)
CAS:133550-30-8
Purity:99% Package:5Mg, 10Mg, 20Mg, 50Mg
AG 490 Basic information
Product Name:AG 490
Synonyms:(E)-2-CYANO-3-(3,4-DIHYDROPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE;A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMAMIDE;A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE;AG 490;ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE;2-CYANO-3-[3,4-DIHYDROXYPHENYL]-N-[PHENYLMETHYL]-2-PROPENAMIDE;N-BENZYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMIDE;N-BENZYL-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE
CAS:133550-30-8
MF:C17H14N2O3
MW:294.3
EINECS:
Product Categories:Protein Kinase;Intracellular Signaling;Inhibitor
Mol File:133550-30-8.mol
AG 490 Structure
AG 490 Chemical Properties
density 1.337
storage temp. −20°C
solubility ethanol: 5 mg/mL
form solid
color yellow
Safety Information
Hazard Codes Xi,N,T
Risk Statements 36/37/38-50-25
Safety Statements 26-36-61-45
WGK Germany 1
MSDS Information
ProviderLanguage
SigmaAldrich English
AG 490 Usage And Synthesis
UsageAG 490 is a potent epidermal growth factor receptor kinase autophosphorylation inhibitor with an IC50 of 100 nM and 56.8 μM for EGFR and JAK, respectively.
Biological ActivitySelective inhibitor of EGF receptor tyrosine kinase (IC 50 values are 2 and 13.5 μ M for EGFR and ErbB2 respectively). Inhibitor of JAK2, JAK3/STAT, JAK3/AP-1 and JAK3/MAPK pathways and potently inhibits cytokine-independent cell growth in vitro and tumor cell invasion in vivo .
AG 490 Preparation Products And Raw materials
Tag:AG 490(133550-30-8) Related Product Information
Stattic WORTMANNIN 1,9-Pyrazoloanthrone PD 98059 SB 203580 LY 294002 HYDROCHLORIDE Tyrphostin AG 490 (N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide) Tyrphostin AG 490 (N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide) (A) TYRPHOSTIN AG 490, 99+%,AG 490,TYROPHOSTIN AG490,TYRPHOSTIN AG 490 TYRPHOSTIN AG 835 AURORA 12314 OTAVA-BB BB7015051722 OTAVA-BB BB7015051721 TYRPHOSTIN B44 AG 490