Company Name: | J & K SCIENTIFIC LTD. |
Tel: | 400-666-7788 +86-10-82848833 |
Email: | jkinfo@jkchemical.com;market3@jkchemical.com |
Products Intro: |
Product Name:CalciuM Ionophore A23187, froM StreptoMyces chartreusis CAS:52665-69-7 Purity:98% Package:5MG |
Company Name: | Meryer (Shanghai) Chemical Technology Co., Ltd. |
Tel: | +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing) |
Email: | sh@meryer.com |
Products Intro: |
Product Name:A23187, free acid CAS:52665-69-7 Purity:98% Remarks:32808 |
Company Name: | 3B Pharmachem (Wuhan) International Co.,Ltd. |
Tel: | 86-21-50328103 * 801、802、803、804 Mobile:18930552037 |
Email: | 67055399@qq.com |
Products Intro: |
Product Name:A23187, free acid;5-(MethylaMino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-triMethyl-8-[(1S)-1-Methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]Methyl]-4-benzoxazolecarboxylicacid CAS:52665-69-7 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g |
Company Name: | Wuhan Chemwish Technology Co., Ltd |
Tel: | 86-027-67849912 |
Email: | sales@chemwish.com |
Products Intro: |
Product Name:6-ForMyl-uracilMonohydrate CAS:52665-69-7 Purity:98% Package:1g;5g;25g;50g;100g;500g |
Company Name: | Ascent Scientific |
Tel: | 4401179829988 |
Email: | customerservice@ascentscientific.co.uk |
Products Intro: |
Product Name:A23187;calcimycin CAS:52665-69-7 Purity:>99% Package:10mg;50mg Remarks:Ca2+ ionophore |
|
Product Name: | A23187 | Synonyms: | CALCIUM IONOPHORE III;CALCIUM IONOPHORE A23187;CALCIMYCIN;CALCIMYCIN A23187;IONOPHORE A-23187;4-BENZOXAZOLECARBOXYLIC ACID, 5-(METHYLAMINO)-2-((3,9,11-TRIMETHYL-8-(1-METHYL-2-OXO-2-(1H-PYRROL-2-YL)ETHYL)-1,7-DIOXASPIRO(5.5)UNDEC-2-YL)METHYL)-(6S-(6ALPHA(2S*,3S*),8BETA(R),9BETA,11ALPHA))-;5-(METHYLAMINO)-2-[[[2R,3R,6S,8S,9R,11R]-3,9,11-TRIMETHYL-8-[(1S)-1-METHYL-2-OXO-2-(1H-PYRROL-2-YL)-ETHYL]-1,7-DIOXASPIRO[5.5]UNDEC-2-YL]METHYL]-4-BENZOXAZOLECARBOXYLIC ACID;A23187 | CAS: | 52665-69-7 | MF: | C29H37N3O6 | MW: | 523.62 | EINECS: | 258-084-1 | Product Categories: | Calcium channel;Signalling;antibiotic | Mol File: | 52665-69-7.mol | |
| A23187 Chemical Properties |
mp | 187-190 °C
| storage temp. | 2-8°C
| Merck | 13,1639 |
| A23187 Usage And Synthesis |
Chemical Properties | white to off-white solid | Usage | Calcimycin is a potent calcium ionophore isolated from Streptomyces chartreusis in 1974. Calcimycin is a spiroketal substituted by pyrollic and benzoxazolyl groups which afford its high affinity and selectivity for calcium. Calimycin exhibits broad biological activity against bacteria, fungi and protozoa. It has found wide application as a research tool for calcium-regulated cellular events. | Usage | Calcimycin is a potent calcium ionophore isolated from Streptomyces chartreusis in 1974. Calcimycin is a spiroketal substituted by pyrollic and benzoxazolyl groups which afford its high affinity and selectivity for calcium. Calcimycin exhibits broad biological activity against bacteria, fungi and protozoa. It has found wide application as a research tool for calcium-regulated cellular events. | Biological Activity | Calcium ionophore that induces Ca 2+ -dependent cell death by increasing intracellular calcium concentration. Promotes intracelllular ROS generation and platelet particle formation (fragmentation) in vitro and in vivo . |
| A23187 Preparation Products And Raw materials |
|