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GW0742

GW0742 Suppliers list
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:GW0742
CAS:317318-84-6
Package:50Mg,5Mg
Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel:86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email:67055399@qq.com
Products Intro: Product Name:GW0742
CAS:317318-84-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name:Chemsky（shanghai）International Co.,Ltd.   
Tel:021-50135380
Email:shchemsky@sina.com
Products Intro: Product Name:GW0742
CAS:317318-84-6
Purity:99% Package:7597RMB/50mg
Company Name:Chemsky（shanghai）International Co.,Ltd.  
Tel:021-50135380
Email:shchemsky@sina.com
Products Intro: Product Name:GW0742
CAS:317318-84-6
Purity:98%
Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD  
Tel:021-20337333/400-620-6333
Email:sale@aladdin-e.com
Products Intro: Product Name:GW0742
CAS:317318-84-6
Purity:99% Package:50MG,10MG
GW0742 Basic information
Product Name:GW0742
Synonyms:GW0742;[4-[[[2-[3-FLUORO-4-(TRIFLUOROMETHYL)PHENYL]-4-METHYL-5-THIAZOLYL]METHYL]THIO]-2-METHYLPHENOXY]ACETIC ACID;4-[2-(3-FLUORO-4-TRIFLUOROMETHYL-PHENYL)-4-METHYL-THIAZOL-5-YLMETHYLSULFANYL]-2-METHYL-PHENOXY-ACETIC ACID;4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]AceticAcid;4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acid;Acetic acid, 2-[4-[[[2-[3-fluoro-4-(trifluoroMethyl)phenyl]-4-Methyl-5-thiazolyl]Methyl]thio]-2-Methylphenoxy]-;2-(4-(((2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy);GW 0742X
CAS:317318-84-6
MF:C21H17F4NO3S2
MW:471.49
EINECS:
Product Categories:All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Inhibitor
Mol File:317318-84-6.mol
GW0742 Structure
GW0742 Chemical Properties
mp 134.5-135.5 °C
storage temp. 2-8°C
solubility DMSO: >5 mg/mL
form solid
color white
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
GW0742 Usage And Synthesis
Chemical PropertiesLight Yellow Solid
UsageA small molecule agonist of the human Peroxisome Proliferator-Activated Recept d (PPAR d). It shows an EC50 of 1.1 nM against PPAR d with 100-fold selectivity over the other human subtypes
UsageA small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.
Biological ActivityPotent and highly selective PPAR δ agonist. EC 50 values are 0.001, 1.1 and 2 μ M for transactivation of human PPAR δ , - α , and - γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.
GW0742 Preparation Products And Raw materials
Tag:GW0742(317318-84-6) Related Product Information
WY-14643 AZD 6244 A 205804 T0070907 Erteberel (LY500307) 4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide (2-METHYLPHENOXY)ACETIC ACID GW0742 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid