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| Products Intro: |
Product Name:K252b
CAS:99570-78-2
Purity:>97% Package:0.25Mg,2.5Mg |
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| Products Intro: |
Product Name:K-252B
CAS:99570-78-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g |
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| Products Intro: |
Product Name:K-252B
CAS:99570-78-2
|
| Company Name: | ChemStrong Scientific Co.,Ltd |
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| Products Intro: |
Product Name:K252A
CAS:99570-78-2
Purity:>98% by HPLC Package:0.5mg,2.5mg |
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| Product Name: | K-252B | | Synonyms: | PROTEIN KINASE INHIBITOR K-252B;K-252B;K-252B, NOCARDIOPSIS SP;K-252B, NOCARDIOPSIS SPECIES;K252B READY MADE;k-252b solution;(9R,10S,12S)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid;Antibiotic K 252b | | CAS: | 99570-78-2 | | MF: | C26H19N3O5 | | MW: | 453.452 | | EINECS: | | | Product Categories: | Antibiotics G-MSerine/Threonine Kinase Biology;Antibiotics;Antibiotics A to;Protein Kinase C (PKC);Serine/Threonine Kinase Inhibitors;Protein Kinase;antibiotic | | Mol File: | 99570-78-2.mol |  |
| | K-252B Chemical Properties |
| storage temp. | −20°C
| | form | ready-to-use solution
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| | K-252B Usage And Synthesis |
| Chemical Properties | Yellow solid | | Usage | K252A is a staurosporine analogue isolated from a Nocardiopsis strain as a potent inhibitor of protein kinase C. K252A exhibits potent antitumour activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents. While K252A is a potent inhibitor of Ca2+/calmodulin kinase II, it is also active against other kinases, notably myosin light chain kinase, cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and cGMP-dependent protein kinase (PKG). | | Usage | K252A is a staurosporine analogue isolated from a Nocardiopsis strain as a potent inhibitor of protein kinase C. K252A exhibits potent antitumor activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents. While K252A is a potent inhibitor of Ca2+/calmodulin kinase II, it is also active against other kinases, notably myosin light chain kinase, cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and cGMP-dependent protein kinase (PKG). |
| | K-252B Preparation Products And Raw materials |
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