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18162-48-6
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ZAPRINAST
ZAPRINAST Suppliers list
Company Name:
J & K SCIENTIFIC LTD.
Tel:
400-666-7788 +86-10-82848833
Email:
jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro:
Product Name:Zaprinast
CAS:37762-06-4
Purity:>99% Package:100Mg,1g
Company Name:
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:
86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email:
67055399@qq.com
Products Intro:
Product Name:Zaprinast;2-(2-Propyloxyphenyl)-8-azapurin-6-one
CAS:37762-06-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name:
Chemsky(shanghai)International Co.,Ltd.
Tel:
021-50135380
Email:
shchemsky@sina.com
Products Intro:
Product Name:Zaprinast
CAS:37762-06-4
Purity:98%
Company Name:
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel:
+86 (21) 51613915
Email:
sales@sunwaypharm.com
Products Intro:
Product Name:ZAPRINAST
CAS:37762-06-4
Company Name:
Spectrum Chemical Manufacturing Corp.
Tel:
021-67601398-808
Email:
gduan@spectrumchina.net
Products Intro:
Product Name:Zaprinast
CAS:37762-06-4
Package:10MG Remarks:Z3001
ZAPRINAST Basic information
Product Name:
ZAPRINAST
Synonyms:
1,4-DIHYDRO-5-[2-PROPOXYPHENYL]-7H-1,2,3-TRIAZOLO[4,5-D]PYRIMIDINE-7-ONE
;
2-(2-PROPYLOXYPHENYL)-8-AZAPURIN-6-ONE
;
M AND B 22948
;
M-EPSILON-TB22948
;
ZAPRINAST
;
2-(2-Propoxyphenyl)-6-hydroxy-8-azapurine
;
1,4-dihydro-5-(2-propoxyphenyl)-7h-1,2,3-triazolo(4,5-d)pyrimidin-7-one
;
2-(2-Propoxyphenyl)-8-azahypoxanthine
CAS:
37762-06-4
MF:
C13H13N5O2
MW:
271.27
EINECS:
253-655-1
Product Categories:
All Inhibitors
;
Inhibitors
;
Intermediates & Fine Chemicals
;
Pharmaceuticals
;
Cyclic Nucleotide related
Mol File:
37762-06-4.mol
ZAPRINAST Chemical Properties
mp
237-238°C dec.
storage temp.
Store at RT
solubility
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.11 mg/mL
form
solid
color
white
Safety Information
Hazard Codes
Xi
Risk Statements
36/37/38
Safety Statements
26-36
WGK Germany
3
MSDS Information
Provider
Language
SigmaAldrich
English
ZAPRINAST Usage And Synthesis
Chemical Properties
Yellow-Orange Crystalline Powder
Usage
cGMP phosphodiesterase inhibitor
Usage
A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of at rial natriuretic factor (ANF) through the activation of PKG (cGMP dependent protein kinase), such inhibitors may display vasodilating, relaxant, and diuretic effects. These compounds may prove useful in treating hypertension and congestive heart failure.
Biological Activity
Phosphodiesterase inhibitor, selective for PDE6, 5, 11 and 9 (IC 50 values are 0.15, 0.76, 12.0 and 29.0 μ M respectively).
ZAPRINAST Preparation Products And Raw materials
Tag:
ZAPRINAST(37762-06-4)
Related Product Information
2-METHOXY-BENZAMIDINE HCL
SALICYLALDEHYDE HYDRAZONE
1H-[1,2,3]TRIAZOL-4-YLMETHYLAMINE HCL
N-[(2-METHOXYPHENYL)METHYLENE]-N-METHYLAMINE
2-PROPOXY-BENZAMIDINE
2-ETHOXY-BENZAMIDINE
ZAPRINAST
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