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Product Name:L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonicacid,2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-Methylene-12-(phenylMethyl)-,11-acetate 5-[(2E,4S,6S)-4,6-diMethyl-2-octenoate], (7S)- CAS:142561-96-4
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Products Intro: |
Product Name:Zaragozic acid A CAS:142561-96-4 Purity:>98% by HPLC Package:1mg,5mg |
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| ZARAGOZIC ACID A Basic information |
Product Name: | ZARAGOZIC ACID A | Synonyms: | ZARAGOZIC ACID A;Squalestatin 1;Aids111671;Aids-111671;Gr 105155x;L-Erythro-L-glycero-D-altro-7-trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-;Squalestatin A, Squalestatin S1, L 694599 | CAS: | 142561-96-4 | MF: | C39H54O13 | MW: | 730.843 | EINECS: | | Product Categories: | | Mol File: | 142561-96-4.mol | |
| ZARAGOZIC ACID A Chemical Properties |
| ZARAGOZIC ACID A Usage And Synthesis |
Usage | Zaragozic acid A is the major metabolite of a class of unusual bicyclic tricarboxylic acids, produced by a number of fungi in the genera Curvularia, Exserohilum, Setosphaeria and others, discovered at Merck and Glaxo in the early 1990s. In nature, zaragozic acid A acts as broad spectrum antifungal but its mode of action as an inhibitor of squalene synthase, involved in sterol biosynthesis, lead to investigation as a cholesterol lowering agent. Zaragozic acid A prepared by BioAustralis is presented as the free acid rather than the tri-sodium salt to avoid stability problems associated with hydrolysis of the salt. | Usage | Zaragozic acid A is the major metabolite of a class of unusual bicyclic tricarboxylic acids, produced by a number of fungi in the genera Curvularia, Exserohilum, Setosphaeria and others, discovered at Merck and Glaxo in the early 1990s. In nature, zaragozic acid A acts as a broad spectrum antifungal but its mode of action as an inhibitor of squalene synthase, involved in sterol biosynthesis, led to investigation as a cholesterol lowering agent. Zaragozic acid A prepared by BioAustralis is presented as the free acid rather than the tri-sodium salt to avoid stability problems associated with hydrolysis of the salt. |
| ZARAGOZIC ACID A Preparation Products And Raw materials |
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