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Product Name:Go 6976
CAS:136194-77-9
Package:1mg, 5mg |
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Product Name:Go 6976;5,6,7,13-Tetrahydro-13-Methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile
CAS:136194-77-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g |
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| Products Intro: |
Product Name:GO-6976
CAS:136194-77-9
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| Products Intro: |
Product Name:Go 6976
CAS:136194-77-9
Purity:98% Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g |
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| | GO 6976 Basic information |
| Product Name: | GO 6976 | | Synonyms: | 12-(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO(2,3-A)PYRROLO(3,4-C)-CARBAZOLE;12-2(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE;GO 6976;G6976;GOE 6976;Go 6976, 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole;12H-Indolo[2,3-A]pyrrolo[3,4-C]carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-;Aids044729 | | CAS: | 136194-77-9 | | MF: | C24H18N4O | | MW: | 378.43 | | EINECS: | | | Product Categories: | Inhibitor | | Mol File: | 136194-77-9.mol |  |
| | GO 6976 Chemical Properties |
| | GO 6976 Usage And Synthesis |
| Biological Activity | Potent protein kinase C (PKC) inhibitor (IC 50 = 7.9 nM). In vitro, discriminates between Ca 2+ -dependent and -independent isoforms of PKC; selectively inhibits PKC α and PKC β 1 (IC 50 values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKC δ , - ε , or - ζ (IC 50 > 3 μ M). Also inhibits TrkA, TrkB, JAK2 and JAK3 tyrosine kinases (IC 50 values are 5, 30, 130 and 370 nM respectively). |
| | GO 6976 Preparation Products And Raw materials |
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