|
CAS番号. | 58880-19-6 |
化学名: | トリコスタチンA |
别名: | トリコスタチンA;(2E,4E,6R)-4,6-ジメチル-7-オキソ-7-[4-(ジメチルアミノ)フェニル]-2,4-ヘプタジエンヒドロキシム酸;(2E,4E,6R)-4,6-ジメチル-7-[4-(ジメチルアミノ)フェニル]-7-オキソ-2,4-ヘプタジエンヒドロキシム酸;(2E,4E,6R)-7-[4-(ジメチルアミノ)フェニル]-N-ヒドロキシ-4,6-ジメチル-7-オキソ-2,4-ヘプタジエナミド |
英語化学名: | TRICHOSTATIN A |
英語别名: | TSA;A 300I;TRICHOSTATIN A;(R)-Trichostatin A;Trichostatin A (TSA);Trichostatin A, Streptomyces sp.;TRICHOSTATIN A FROM STREPTOMYCES SP;Trichostatin A, Ready Made Solution;TRICHOSTATIN A, STREPTOMYCES SPECIES;Trichostatin A from Streptomyces platensis |
CBNumber: | CB8257301 |
分子式: | C17H22N2O3 |
分子量: | 302.37 |
MOL File: | 58880-19-6.mol |
|
|
|
|
トリコスタチンA 物理性質 |
|
|
屈折率 : |
136 ° (C=0.3, MeOH) |
|
|
solubility : |
ethanol: 1 mg/mL
|
|
|
|
トリコスタチンA 化学特性,用途語,生産方法 |
|
使用
Trichostatin A is a known inhibitor of fibrosis in vitro and in vivo, and is used as an anticancer agent. Potent differentiation inducer of friend leukemic cells. |
|
使用
Trichostatin A is a histone deacetylase inhibitor that enhances the cytotoxic efficacy of anticancer drugs that target DNA. Trichostatin A displays antifungal, antiprotozoan and antitumour activity |
|
使用
Trichostatin A is a histone deacetylase inhibitor that enhances the cytotoxic efficacy of anticancer drugs that target DNA. Trichostatin A displays antifungal, antiprotozoan and antitumor activity |
|
生物活性
Selective and potent inhibitor of histone deacetylase (K i = 3.4 nM). Active in vivo . Potential anti-cancer agent. Induces accelerated dedifferentiation of primordial germ cells (PGCs) into embryonic germ (EG) cells. |
|
|
トリコスタチンA 上流と下流の製品情報 |
原材料
|
準備製品
|
トリコスタチンA 生産企業 Global( 86)Suppliers |
|
|
|
|
58880-19-6
(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE
7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE
4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXAHEPTA-2,4-DIENOHYDROXAMIC ACID
4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXOHEPTA-2,4-DIENOHYDROXAMIC ACID
7-(4-(dimethylamino)phenyl)-n-hydroxy-4,6-dimethyl-7-oxo-4-heptadienamide
TSA
TRICHOSTATIN A
TRICHOSTATIN A, STREPTOMYCES SPECIES
Trichostatin A, Streptomyces sp.
2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-
TRICHOSTATIN A FROM STREPTOMYCES SP
Trichostatin A from Streptomyces platensis
[r-(e,e)]-7-[4-(dimethylamino)phenyl]-n-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE
TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
(2E,4E,6R)-4,6-Dimethyl-7-[4-(dimethylamino)phenyl]-7-oxo-2,4-heptadienehydroximic acid
(2E,4E,6R)-4,6-Dimethyl-7-oxo-7-[4-(dimethylamino)phenyl]-2,4-heptadienehydroximic acid
Trichostatin A,TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
(R)-Trichostatin A
Trichostatin A (TSA)
A 300I
(R,2E,4E)-6-(4-(dimethylamino)benzoyl)-N-hydroxy-4-methylhepta-2,4-dienamide
Trichostatin A, Ready Made Solution
トリコスタチンA
(2E,4E,6R)-4,6-ジメチル-7-オキソ-7-[4-(ジメチルアミノ)フェニル]-2,4-ヘプタジエンヒドロキシム酸
(2E,4E,6R)-4,6-ジメチル-7-[4-(ジメチルアミノ)フェニル]-7-オキソ-2,4-ヘプタジエンヒドロキシム酸
(2E,4E,6R)-7-[4-(ジメチルアミノ)フェニル]-N-ヒドロキシ-4,6-ジメチル-7-オキソ-2,4-ヘプタジエナミド
生化学
試験研究用抗腫瘍剤
阻害剤
|