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| CAS番号. | 6055-19-2 |
| 化学名: | シクロフォスファミド |
| 别名: | シクロホスファミド一水和物;シクロホスファミドモノハイドレイト;サイクロホスフアミド;シクロフォスファミド |
| 英語化学名: | Cyclophosphamide monohydrate |
| 英語别名: | CPA;ENDOXON;CYTOXAN;Procy-tox;Cycloblastin;-2monohydrate;endoxanmonohydrate;TIMTEC-BB SBB003026;cyclophosphamide，CTX;Cyclophosphamide mon |
| CBNumber: | CB5345867 |
| 分子式: | C7H17Cl2N2O3P |
| 分子量: | 279.1 |
| MOL File: | 6055-19-2.mol |
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| シクロフォスファミド 物理性質 |
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| solubility : |
H2O: 0.1 g/mL, clear, colorless
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シクロフォスファミド 化学特性,用途語,生産方法 |
化学的特性
White to Off-White Solid |
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使用
It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen. |
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使用
antineoplastic, alkylating agent |
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使用
alkylating agent in cancer therapy |
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一般的な説明
Fine white crystalline powder with a slightly bitter taste. Little or no odor. |
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空気と水の反応
Water soluble. Sensitive to moisture and light. Aqueous solutions may be kept for a few hours above room temperature, but hydrolysis occurs at temperatures above 86°F. Cyclophosphamide monohydrate undergoes both specific acid and specific base catalysis at extreme pHs. Spontaneous hydrolysis in aqueous solutions. |
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反応プロフィール
Polymerization can occur at temperatures > 120° F. Cyclophosphamide monohydrate reacts with strong oxidizing agents, strong acids and strong bases. Benzyl alcohol increases rate of hydrolysis. |
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火災危険
Cyclophosphamide monohydrate is probably combustible. |
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| シクロフォスファミド 生産企業 Global( 152)Suppliers |
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6055-19-2
(bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide
1-bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridinemonohydrate
2-(bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane2-oxidemonohydr
2-(di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane-2-oxidemonohydra
2h-1,3,2-oxazaphosphorine,tetrahydro-2-(bis(2-chloroethyl)amino)-,2-oxide,mo
-2monohydrate
cyclicn’,o-propyleneesterofn,n-bis(2-chloroethyl)phosphorodiamidicacidm
endoxanmonohydrate
n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxaphosphorin-2-amine,2-oxidemono
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphos-phorin-2-amine2-oxide
n,n-bis(beta-chloroethyl)-n’,o-propylenephosphoricacidesteramidemonohydra
n,n-bis(beta-chloroethyl)-n’,o-trimethylenephosphoricacidesterdiamidemono
n,n-bis(beta-cloraethyl)n’-o-propylenphosphorildiamidmonohydratum
N,N-Bis-2-chloroethyl-N’,O-propylenephosphoricesterdiamidemonohydrate
n,n-di(2-chloroethyl)amino-n,o-propylenephosphoricacidesterdiamidemonohy
Procy-tox
CPA
ENDOXON
CYTOXAN
CYCLOPHOSPHAMIDE HYDRATE
CYCLOPHOSPHAMIDE MONOHYDRATE
CYCLOPHOSPHAMID MONOHYDRATE
bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate
2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE
2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE HYDRATE
2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE MONOHYDRATE
N,N-BIS(2-CHLOROETHYL)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORIN-2-AMINE-2-OXIDE MONOHYDRATE
n,n-bis(beta-chloroethyl)-n',o-propylenephosphoric acid ester amide monohydrate
TIMTEC-BB SBB003026
> 100 Kgyclophosphamide monohydrate
シクロホスファミド一水和物
シクロホスファミドモノハイドレイト
サイクロホスフアミド
シクロフォスファミド
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