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Tamoxifen

CAS No.10540-29-1
Chemical Name:Tamoxifen
Synonyms:Genox;C07108;Tamoxen;ici47699;Mammaton;Novaldex;TAMOXIFEN;Nolvadex-D;TaMoxiefen;z-tamoxifen
CBNumber:CB9438781
Molecular Formula:C26H29NO
Formula Weight:371.51
MOL File:10540-29-1.mol
Tamoxifen Property
mp : 97-98 °C(lit.)
storage temp. : 2-8°C
Merck : 13,9137
CAS DataBase Reference: 10540-29-1(CAS DataBase Reference)
EPA Substance Registry System: Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1- butenyl]phenoxy]-N,N-dimethyl- (10540-29-1)
Safety
Hazard Codes : T,Xi
Risk Statements : 45-60-61-64-36/37/38
Safety Statements : 53-45-36-26
WGK Germany : 3
RTECS : KR5919600
Hazardous Substances Data: 10540-29-1(Hazardous Substances Data)

Tamoxifen Chemical Properties,Usage,Production

Chemical Properties
White Crystalline Solid
Usage
A nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a Protein Kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines
Usage
Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen Preparation Products And Raw materials
Raw materials
Preparation Products
Tamoxifen Suppliers      Global( 78)Suppliers     
SupplierTelFaxEmailCountryProdListAdvantage
Wuhan DKY Technology Co.,Ltd. 027-81302011 15347069687027-81302088sales@whdky.com;2851686510@qq.comCHINA 2019 58
Chembest Research Laboratories Limited +86(0)21-20908456+86(0)21-58180499sales@biochembest.comCHINA 6000 61
Adamas Reagent, Ltd. 400-600-9262021-51701678mc@titansci.comCHINA 13697 59
Chemfun Medical Technology(Shanghai) Co., Ltd. 021-67220633 & 021-37212706+86-21-67220638chemfun@chemfun.netCHINA 21915 59
LGM Pharma 1-(800)-881-8210615-250-9817inquiries@lgmpharma.comUSA 1972 70
Nanjing Chemlin Chemical Co., Ltd 025-83697070; 010-68547217+86-25-83453306sales@chemlin.com.cnCHINA 20120 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.comCHINA 298 58
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.comCHINA 32553 50
Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;+86 (531) 55696010 QQ981200479sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)CHINA 1779 62
Syntechem Co.,Ltd info@syntechem.com QQ 421151915E-Mail Inquiryinfo@syntechem.comCHINA 13109 57
 
10540-29-1(Tamoxifen)Related Search:
TAMOXIFEN, 4-HYDROXY-, (Z)-,TAMOXIFEN, (Z)-4-HYDROXY- Toremifene cis-α-Hydroxy Tamoxifen TAMOXIFEN, [N-METHYL-3H]- Chlorodiphenylphosphine Diphenyldimethoxysilane Dimethyldimethoxysilane Diphenylsilane tert-Butylchlorodiphenylsilane TAMOXIFEN CITRATE,TAMOXIFEN CITRATE SALT phenoxybenzamine Diphenylphosphine Diphenyldiethoxysilane trans,trans-2,4-Undecadienal Tamoxifen Biphenyl TRANSFAT TAMOXIFEN CITRATE(RG)
(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)phenoxy)-n,n-dimethylethanamine (z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylamine 1-para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene 1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene ici47699 n-dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-(z)-ethylamin Nolvadex-D tamoxifen(z) tamoxifendrugstandardsolution trans-tamoxifen z-tamoxifen Antibiotics T-Z 10540-29-1 Antibiotics A to Z Antibiotics BioChemical TAMOXIFEN TAMOXIFEN BASE TRANS-2-[4-(1,2-DIPHENYL-1-BUTENYL)PHENOXY]-N,N-DIMETHYLETHYLAMINE (Z)-2-[4-(1,2-DIPHENYL-1-BUTENYL)PHENOXY]-N,N-DIMETHYLETHANAMINE [Z]-1-[P-DIMETHYLAMINOETHOXYPHENYL]-1,2-DIPHENYL-1-BUTENE Genox Tamoxen tamoxifen free base C26H29NO Ethanamine, 2-4-(1Z)-1,2-diphenyl-1-butenylphenoxy-N,N-dimethyl- Active Pharmaceutical Ingredients Protein Kinase Inhibitors and Activators Intermediates & Fine Chemicals Pharmaceuticals Isotope Labeled Compounds C2514CH29NO (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene, trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine C6H5CC2H5CC6H5C6H4OCH2CH2NCH32 C25H27NOHCl 2-[4-[(Z)-1,2-Di(phenyl)but-1-enyl]phenoxy]-N,N-dimethylethanamine Mammaton 2-[4-[(Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine 2-[p-[(Z)-1,2-Diphenyl-1-butenyl]phenyloxy]-N,N-dimethylethanamine N,N-Dimethyl-2-[p-[(Z)-1,2-diphenyl-1-butenyl]phenoxy]ethanamine C26H28NO C07108 Tamoxifen,(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene, trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine 1-p-β-DiMethylaMinoethoxyphenyl-trans-1,2-diphenylbut-1-ene Aromatics Novaldex (Z)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-diMethylethanaMine TaMoxiefen EthanaMine,2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-diMethyl-
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