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Pravastatin sodium

CAS No.81131-70-6
Chemical Name:Pravastatin sodium
Synonyms:Prava;ELISOR;cs-514;Vasten;sq31000;Lipidal;lipostat;KOPOSTAT;Liprevil;Pravacol
CBNumber:CB9317123
Molecular Formula:C23H36NaO7
Formula Weight:447.52
MOL File:81131-70-6.mol
Pravastatin sodium Property
mp : 171.2-173 °C
storage temp. : 2-8°C
solubility : H2O: 19 mg/mL
form : powder
color : white
CAS DataBase Reference: 81131-70-6(CAS DataBase Reference)
Safety
Hazard Codes : F,C
Risk Statements : 11-34
Safety Statements : 16-26-36/37/39-45
RIDADR : 3077
WGK Germany : 2
RTECS : QJ7185000
HazardClass : 9
PackingGroup : III

Pravastatin sodium Chemical Properties,Usage,Production

Chemical Properties
White Crystalline Powder
Usage
A competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of Mevastatin
Usage
antihyperlipidemic, HMGCoA reductase inhibitor
Usage
Pravastatin sodium is the salt of pravastatin, a ring-opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of microorganisms, notably Absidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a β-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoAreductase inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges.
Usage
An HMGCR inhibitor which blocks cholesterol synthesis
Biological Activity
Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (K i ~ 1 nM) and displays cardioprotective properties.
Pravastatin sodium Preparation Products And Raw materials
Raw materials
Preparation Products
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81131-70-6(Pravastatin sodium)Related Search:
Sodium formate Sodium carbonate Sodium gluconate Sodium benzoate Pravastatin Diclofenac sodium Sodium acetate Sodium hydroxide Sodium bicarbonate Sodium chlorate Sodium chlorite Fluvastatin sodium salt ATORVASTATIN SODIUM 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Sodium chloride Sodium citrate Pravastatin sodium Sodium percarbonate
1-naphthaleneheptanoicacid,1,2,6,7,8,8a-hexahydro-2-methyl-8-(2-methyl-1-oxob 2-alpha,6-alpha,8-beta(r*),8a-alpha))-* cs-514 epastatinsodium lipostat sq31000 utoxy)-beta,delta,6-trihydroxy-,monosodiumsalt,(1s-(1-alpha(beta-s*,delta-s KOPOSTAT MEVALOTIN ELISOR EPTASTATIN SODIUM (BETA R,DELTA R,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8-[(2S)-2-METHYL-1-OXOBUTOXY]-1-NAPHTHALENEHEPTANOIC ACID MONOSODIUM SALT (BETAR, DELTAR,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA, DELTA,6-TRIHYDROXY-2-METHYL-8[(2S)-2-METHYL-1-OXOBUTOXYL]-1-NAPHTHALENEHEPTANOIC ACID SODIUM (BETA-R,DELTA-R,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8[(2S)-2-METHYL-1-OXOBUTOXYL]-1-NAPHTHALENEHEPTANOIC ACID NA Biochemicals and Reagents BioChemical 81131-70-6 3BETA-HYDROXYCOMPACTIN, NA PRAVASTATIN SODIUM SALT PRAVASTATIN SODIUM PRAVASELECT PRAVACHOL Enzymes, Inhibitors, and Substrates D to K Enzyme Inhibitors Enzyme Inhibitors by Enzyme Hydroxymethylglutaryl-CoA Reductase Pravastatin Sodium (US Pat 1981) Paravastatin PravastatinNaC23H35Na07 1-Naphthaleneheptanoicacid Pravastatine Pravastatinesodium C23H35O7Na Elisor, Kopostat, Mevalotin, Pravachol, Pravaselect, C23H35NaO7 Eptastatin 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-.beta.,.delta.,6-trihydroxy-2-methyl-8-(2S)-2-methyl-1-oxobutoxy-, monosodium salt, (.beta.R,.delta.R,1S,2S,6S,8S,8aR)- (βr, δr,1s,2s,6s,8s,8ar)-1,2,6,7,8,8a-hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2s)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic acid sodium 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, monosodium salt, [1S-[1a(bS*,dS*),2a,6a,8b(R*),8aa]]- 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-b,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, monosodium salt, (bR,dR,1S,2S,6S,8S,8aR)- (9CI) 3b-Hydroxycompactin sodium salt Lipidal Liprevil Oliprevin Prava Pravacol Pravasin Pravasine Selektine Selipran Vasten Active Pharmaceutical Ingredients [1S-[1a(bS,dS),2a,6b,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic acid monosodium salt Antihyperlipoproteinemic Pravastatinsodium,(S) Various Metabolites and Impurities (R,dR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt
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