KU-55933 (ATM Kinase Inhibitor)

CAS No.	587871-26-9
Chemical Name:	KU-55933 (ATM Kinase Inhibitor)
Synonyms:	KV-55933;KU-55933, >99%;KU-55933 (ATM Kinase Inhibitor);2-MORPHOLIN-4-YL-6-THIANTHREN-1-YL-PYRAN-4-ONE;2-morpholino-6-(thianthren-1-yl)-4H-pyran-4-one;2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one;2-Morpholin-4-yl-6-thianthren-1-ylpyran-4-one KU-55933 (ATM Kinase Inhibitor)
CBNumber:	CB8503709
Molecular Formula:	C21H17NO3S2
Formula Weight:	395.49
MOL File:	587871-26-9.mol

KU-55933 (ATM Kinase Inhibitor) Property

storage temp. :

Desiccate at -20°C

Safety

KU-55933 (ATM Kinase Inhibitor) Chemical Properties,Usage,Production

Usage
A potent and specific ATM kinase inhibitor with an IC50 and a Ki of 13 nM and 2.2 nM, respectively.

Biological Activity
Potent, selective and competitive ATM kinase inhibitor (K i = 2.2 nM, IC 50 values are 13, 2500, 9300, 16600, > 100000 and > 100000 nM at ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively). Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21 CIP1 levels in vitro . Acts as a radio- and chemosensitizer for the treatment of cancer.

KU-55933 (ATM Kinase Inhibitor) Preparation Products And Raw materials

Raw materials

Preparation Products

KU-55933 (ATM Kinase Inhibitor) Suppliers Global( 53)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078,021-50426030	86-021-50426522,50426273	sales@jingyan-chemical.com	CHINA	10108	60
Chemfun Medical Technology(Shanghai) Co., Ltd.	021-67220633 & 021-37212706	+86-21-67220638	chemfun@chemfun.net	CHINA	21915	59
Chemsky (shanghai) International Co.,Ltd	021-50135380		shchemsky@sina.com	CHINA	15730	60
Jinan Trio PharmaTech Co., Ltd.	+86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;	+86 (531) 55696010 QQ981200479	sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)	CHINA	1779	62
ShangHai Biochempartner Co.,Ltd	+86 13818785766，400-021-9906		gaoqing@biochempartner.com	CHINA	1167	62
China Langchem Inc.	0086-21-58956006,021-58950017;021-38701807	0086-21-58956100	sales@langchem.com	CHINA	11187	57
Shanghai Sunway Pharmaceutical Technology Co., Ltd	+86 (21) 51613915	+86 (21) 51613951	sales@sunwaypharm.com	CHINA	10114	57

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587871-26-9 2-MORPHOLIN-4-YL-6-THIANTHREN-1-YL-PYRAN-4-ONE C21H17NO3S2 2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one KU-55933 (ATM Kinase Inhibitor) KU-55933, >99% KV-55933 2-morpholino-6-(thianthren-1-yl)-4H-pyran-4-one 2-Morpholin-4-yl-6-thianthren-1-ylpyran-4-one KU-55933 (ATM Kinase Inhibitor)