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pipacycline

CAS No.1110-80-1
Chemical Name:pipacycline
Synonyms:Sieromicin;Pipacicline;Mepicycline;pipacycline;Tetrasolvina;(4S)-4β-Dimethylamino-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,6α,10,12,12aβ-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
CBNumber:CB7928471
Molecular Formula:C29H38N4O9
Formula Weight:586.638
MOL File:1110-80-1.mol
pipacycline Property
Safety

pipacycline Chemical Properties,Usage,Production

Usage
Pipacycline (mepicycline) is a semi-synthetic tetracycline formed by a Mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracycline. The introduction of the piperazine improves bioavailability, but Mannich bases are pro-drugs, converting back to the parent compound. Pipacycline is used commercially as a salt in combination with penicillin V for parenteral use (penimepicycline). The intrinsic in vitro activity and SARs for the amide region of the tetracycline molecule have not investigated extensively. Pipacycline has not been extensively cited in the literature.
Usage
Pipacycline (mepicycline) is a semi-synthetic tetracycline formed by a Mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracycline. The introduction of the piperazine improves bioavailability, but Mannich bases are pro-drugs, converting back to the parent compound. Pipacycline is used commercially as a salt in combination with penicillin V for parenteral use (penimepicycline). The intrinsic in vitro activity and SARs for the amide region of the tetracycline molecule have not been investigated extensively. Pipacycline has not been extensively cited in the literature.
pipacycline Preparation Products And Raw materials
Raw materials
Preparation Products
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1110-80-1(pipacycline)Related Search:
Tetracycline (S)-2-METHYL-1-PHENYL-BUT-3-EN-1-OL (S)-1-PHENYL-BUT-3-EN-1-OL Apicycline 4-Methyl-1-tetralone 1,2,3,4-Tetrahydro-1-naphthol 1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL 3-(2-ISOPROPYLPHENYL)-1-PROPENE 1-ACETYL-1-CYCLOHEXENE Sancycline pipacycline
1110-80-1 pipacycline (4S)-4β-Dimethylamino-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,6α,10,12,12aβ-pentahydroxy-N-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Mepicycline Pipacicline Sieromicin Tetrasolvina C29H38N4O9
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