PD 146176 Property |
storage temp. : |
Store at +4°C |
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solubility : |
DMSO: 16 mg/mL, soluble
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PD 146176 Chemical Properties,Usage,Production |
Biological Activity
Specific, non-competitve 15-lipoxygenase (15-LOX) inhibitor (K i = 197nM) that has no demonstrable effect on 5-LOX, 12-LOX, COX-1 or COX-2 (IC 50 = 0.54 μ M for 15-LOX in rabbit reticulocytes). Lacks non-specific antioxidant properties and prevents atherogenesis via regulation of monocyte-macrophage enrichment in vivo . |
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PD 146176 Preparation Products And Raw materials |
Raw materials
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Preparation Products
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PD 146176 Suppliers Global( 8)Suppliers |
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