Topiramate

CAS No.	97240-79-4
Chemical Name:	Topiramate
Synonyms:	Topina;TOPAMAX;Topimax;EpitoMa;TopaMac;TopoMax;MCN 4853;EpitoMax;RWJ 17021;TOPIRAMATE
CBNumber:	CB7402630
Molecular Formula:	C12H21NO8S
Formula Weight:	339.36
MOL File:	97240-79-4.mol

Topiramate Property

mp :

125°C

storage temp. :

2-8°C

solubility :

DMSO: ~44 mg/mL

form :

solid

color :

white

Safety

Hazard Codes :

Xi,T,F

Risk Statements :

36/37/38-39/23/24/25-23/24/25-11

Safety Statements :

26-36-45-36/37-16-7

WGK Germany :

RTECS :

LS7083000

Hazardous Substances Data:

97240-79-4(Hazardous Substances Data)

Topiramate Chemical Properties,Usage,Production

Chemical Properties
White-to-Off-White Crystalline Powder

Usage
anticonvulsant, antimigraine, GABA-A agonist, AMP/kinate glutamate receptor antagonist, carbonic anhydrase inhibitor

Usage
Used for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome. Qsymia? is indicated for the treat

Usage
Used as an anticonvulsant

Biological Activity
Anticonvulsant. Antagonizes GluR5 kainate receptors (IC 50 = 0.46 μ M), acts as a positive allosteric modulator of GABA A receptor-mediated currents, inhibits Na v channels (IC 50 = 48.9 μ M) and inhibits L-type Ca 2+ channels. Also inhibits carbonic anhydrase (CA) (K i values are 0.1 and 0.2 μ M at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.

Topiramate Preparation Products And Raw materials

Raw materials

Preparation Products

Topiramate Suppliers Global( 234)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd	010-64430626/13801208576	010-64215766	maggie@chinazhongshuo.com	CHINA	222	65
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)	+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)	sh@meryer.com	CHINA	40407	62
INTATRADE GmbH	+49 3493/605464	+49 3493/605470	sales@intatrade.de	GERMANY	3590	66
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
TAIYUAN RHF CO.,LTD.	+86 351 7031519	+86 351 7031519	sales@RHFChem.com	CHINA	2366	56
TCI (Shanghai) Development Co., Ltd.	--	--	info@chemicalbook.com	CHINA	22159	81
Energy Chemical	021-58432009 / 400-005-6266	021-58436166-800	info@energy-chemical.com	CHINA	44198	61
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078,021-50426030	86-021-50426522,50426273	sales@jingyan-chemical.com	CHINA	10108	60

97240-79-4(Topiramate)Related Search:

ACY-1215 (E)-N-HYDROXY-3-(4-{[2-(2-METHYL-1H-INDOL-3-YL)-ETHYLAMINO]-METHYL}-PHENYL)-ACRYLAMIDE Lomefloxacin hydrochloride Nisoldipine Entinostat Z-VAD-FMK Sulfamic acid beta-D-Fructopyranose Topiramate hydrochloride 4,5-Desisopropylidene Topiramate 2,3-Desisopropylidene Topiramate Topiramate2,3:4,5-Bis-O-(1-MethylEthylidene)-B- Topiramate Related Compound A TOPIRAMATE-D12 Topiramate 2,3:4,5 Bis-O-(1-Methyl ethylidene)-Fructopyranose azido sulphate 10-Hydroxy Topiramate,R-Hydroxy Topiramate 9-Hydroxy Topiramate,S-Hydroxy Topiramate

2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranossulfamate MCN 4853 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-36-D-FRUCTO-PYRANOSE SULFAMATE 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-B-D-FUCTO-PYRANOSE SULFAMATE 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose sulfamate 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-BETA-D-FUCTOPYRANOSE SULFAMATE BioChemical Cell Biology Cell Signaling and Neuroscience 97240-79-4 RWJ 17021 RWJ-17021-000 Ionotropic Glutamate Receptor Modulators Ion Channels Ligand-Gated Ion Channels TOPIRAMATE TOPAMAX C12H21NO8S 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulfamate 2,3:4,5-Bis-O-(1-methylethylidene)-b-D-fuctopyranose Sulfamate, McN-4853, RWJ-17021-000, Topamax .beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranosidesulfamate C12H21O8NS Active Pharmaceutical Ingredients 95240-79-4 APIs Health & Beauty 2,3:4,5-Bis-O-(1-methylethylidene)--D-fuctopyranose Sulfamate, McN-4853, RWJ-17021-000, Topamax Carbohydrates & Derivatives Pharmaceuticals McN 4853, RWJ 17021, Topamax, 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate Glutamate receptor Topimax Topiramic acid 1-O-Sulfamoyl-2-O,3-O:4-O,5-O-bis(1-methylethylidene)-β-D-fructopyranose 1-O-Sulfamoyl-2-O,3-O:4-O,5-O-diisopropylidene-β-D-fructopyranose Topina C21H21NO8S 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranoside sulfamate Intermediates & Fine Chemicals 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamate Topiramate (150 mg) 2,3:4,5-Bis-O-(1-Methylethylidene)-β-D-fuctopyranose 1-SulfaMate EpitoMa EpitoMax TopaMac TopoMax TopiraMate API 2,3:4,5-Di-O-isopropylidene-1-O-sulfamoyl-beta-D-fructopyranose TopiraMate(McN-4853,RWJ-17021,TopaMax) TopiriMate-d12 API ((3aS,5aR,8aR,8bS)-2,2,7,7-tetraMethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)Methyl sulfaMate TOPAMAX Topiramate Synonyms Topamax β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate Topiramate solution