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EMBELIN

CAS No.550-24-3
Chemical Name:EMBELIN
Synonyms:EMBELIN;emberine;NSC 91874;embelicacid;XIAP INHIBITOR;EMbeliaquinone;TIMTEC-BB SBB005949;APOPTOSIS ACTIVATOR III;embelin from embelia seeds;2,5-dihydroxy-3-undecyl-p-benzoquinon
CBNumber:CB7365074
Molecular Formula:C17H26O4
Formula Weight:294.39
MOL File:550-24-3.mol
EMBELIN Property
mp : 142-143°C
density : 1.131
storage temp. : Store at +4°C
solubility : DMSO: >10 mg/mL
form : solid
Safety
WGK Germany : 3
RTECS : DK4230000

EMBELIN Chemical Properties,Usage,Production

Chemical Properties
Orange Solid
Usage
Embelin is a natural benzoquinone found in plants of the Myrsinaceae family. Embelin has a wide range of biological activity as it inhibits the growth of bacteria, fungi, protozoa and parasites. Embel in also displays contraceptive and pro-apoptotic properties.
Biological Activity
Cell-permeable, non-peptide inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC 50 = 4.1 μ M in competition binding assay with Smac peptide); binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Inhibits cell growth, induces apoptosis and activates caspase-9 in prostate cancer cells (IC 50 4-6 μ M), but has a weaker effect on normal prostate cells (IC 50 = 19-20 μ M). Overcomes the protective effect of XIAP on apoptosis in XIAP-transfected Jurkat cells. Anti-tumor, analgesic and anti-inflammatory in vivo .
EMBELIN Preparation Products And Raw materials
Raw materials
Preparation Products
EMBELIN Suppliers      Global( 58)Suppliers     
SupplierTelFaxEmailCountryProdListAdvantage
Wuhan Chemwish Technology Co., Ltd 86-027-6784991286-027-87531808sales@chemwish.comCHINA 35932 56
Wuhan Chemwish Technology Co.， Ltd 027-67849912027-87531808sales@chemwish.comCHINA 9158 60
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Chembest Research Laboratories Limited +86(0)21-20908456+86(0)21-58180499sales@biochembest.comCHINA 6000 61
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501+86-21-54096319sales@sinch.com.cnCHINA 11621 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.comCHINA 32553 50
Syntechem Co.,Ltd info@syntechem.com QQ 421151915E-Mail Inquiryinfo@syntechem.comCHINA 13109 57
SpringPharma Tech Co.,Ltd +86-25-68710896/ +86-25-68710897025-68710856sales@springpharma.netCHINA 1268 62
Spectrum Chemical Manufacturing Corp. 021-67601398-808021-57711696gduan@spectrumchina.netCHINA 9357 60
 
550-24-3(EMBELIN)Related Search:
MAESAQUINONE RAPANONE ACETIC ACID 4-HYDROXY-2-METHYL-5-((E)-NONADEC-14-ENYL)-3,6-DIOXO-CYCLOHEXA-1,4-DIENYL ESTER 2-HYDROXY-5-METHOXY-6-METHYL-3-((E)-NONADEC-14-ENYL)-[1,4]BENZOQUINONE 2-[13-(3-BUTYL-OXIRANYL)-TRIDECYL]-3,6-DIHYDROXY-5-METHYL-[1,4]BENZOQUINONE 2,5-DIMETHOXY-3-TRIDECYL-[1,4]BENZOQUINONE 2,5-DIMETHOXY-3-UNDECYL-[1,4]BENZOQUINONE ACETIC ACID 4-HYDROXY-3,6-DIOXO-5-UNDECYL-CYCLOHEXA-1,4-DIENYL ESTER EMBELIN 2-HYDROXY-5-METHOXY-3-PENTADECYL-[1,4]BENZOQUINONE 2-HYDROXY-5-METHOXY-3-UNDECYL-[1,4]BENZOQUINONE 2,5-DIHYDROXY-3-PENTADECYL-[1,4]BENZOQUINONE ACETIC ACID 4-ACETOXY-3,6-DIOXO-5-UNDECYL-CYCLOHEXA-1,4-DIENYL ESTER 2-HYDROXY-5-METHOXY-3-TRIDECYL-[1,4]BENZOQUINONE 2,5-DIHYDROXY-3-METHYL-6-NONADECYL-[1,4]BENZOQUINONE 2,5-DIMETHOXY-3-METHYL-6-((E)-NONADEC-14-ENYL)-[1,4]BENZOQUINONE 2,5-DIMETHOXY-3-METHYL-6-NONADECYL-[1,4]BENZOQUINONE ACETIC ACID 4-ACETOXY-2-METHYL-5-((E)-NONADEC-14-ENYL)-3,6-DIOXO-CYCLOHEXA-1,4-DIENYL ESTER
2,5-dihydroxy-3-undecyl-p-benzoquinon 4-dione,2,5-dihydroxy-3-undecyl-5-cyclohexadiene-1 embelicacid emberine APOPTOSIS ACTIVATOR III EMBELIN 550-24-3 2,5-DIHYDROXY-3-UNDECYL-1,4-BENZOQUINONE 2,5-DIHYDROXY-3-UNDECYL-2,5-CYCLOHEXADIENE-1,4-DIONE 2,5-DIHYDROXY-3-UNDECYL-P-BENZOQUINONE Antibiotics Antibiotics A to Z Antibiotics A-F BioChemical TIMTEC-BB SBB005949 XIAP INHIBITOR embelin from embelia seeds 2,5-DIHYDROXY-3-UNDECYL-P-BENZOQUINONE, EMBELIN Anthraquinones, Hydroquinones and Quinones Caspases/Apoptosis 2,5-dihydroxy-3-undecyl-cyclohexa-2,5-diene-1,4-dione 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione NSC 91874 EMbeliaquinone 2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3-undecyl- free base
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