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(Z)-Guggulsterone

CAS No.95975-55-6
Chemical Name:(Z)-Guggulsterone
Synonyms:GUGULSTERONE;GUGGULSTERONE;GUGGULSTERONE Z;GUGGULESTERONE Z;CIS GUGGULSTERONE;(Z)-Guggulsterone;Guggulsterone E&Z;Guggulsterones E&Z;GUGGULISTERONES 95%;(E&Z)-Guggulsterone
CBNumber:CB7309069
Molecular Formula:C21H28O2
Formula Weight:312.45
MOL File:95975-55-6.mol
(Z)-Guggulsterone Property
storage temp. : 2-8°C
solubility : DMSO: 5 mg/mL
form : powder
color : light yellow
CAS DataBase Reference: 95975-55-6(CAS DataBase Reference)
Safety
Hazard Codes : Xi
Risk Statements : 37
Safety Statements : 36
WGK Germany : 3

(Z)-Guggulsterone Chemical Properties,Usage,Production

Biological Activity
Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (K i = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (K i values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR).
(Z)-Guggulsterone Preparation Products And Raw materials
Raw materials
Preparation Products
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95975-55-6((Z)-Guggulsterone)Related Search:
N-BUTYLISOCYANIDE CHROMIUM(III) ACETYLACETONATE COBALT(II) ACETYLACETONATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Ferric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) METHYL ISOCYANOACETATE Aluminum acetylacetonate 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Cupric acetylacetonate PHENYLSELENOL BENZYL ISOCYANIDE (Z)-Guggulsterone Dehydroepiandrosterone Ecdysone TRANS-GUGGULSTERONE,GUGGULSTERONE,GUGGULSTERONE (E FORM),GUGGULSTERONE E,E-GUGGULSTERONE Androsterone Gestodene
CIS-4,17(20)-PREGNADIENE-3,16-DIONE CIS GUGGULSTERONE GUGULSTERONE GUGGULSTERONE Z GUGGULSTERONE (Z FORM) GUGGULESTERONE Z GUGGULSTERONE Alphabetic Analytical Chromatography Product Catalog Analytical Standards 95975-55-6 4,17(20)-(CIS)-PREGNADIEN-3,16-DIONE PREGNA-4,17(20)-DIENE-3,16-DIONE (8S,9R,10R,13S,14S,17E)-17-(1-methoxyethylidene)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione pregna-4,17-diene-3,16-dione GUGGULISTERONES 95% Miscellaneous (17Z)-Pregna-4,17(20)-diene-3,16-dione (Z)-Guggulsterone (17E)-Pregna-4,17(20)-diene-3,16-dione GUGGULSTERONES E&Z(MIX)(FG) GuggulsteronesE&Z(mix) (E&Z)-Guggulsterone Guggulsterone E&Z Guggulsterones E&Z
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