PHA-665752

CAS No.	477575-56-7
Chemical Name:	PHA-665752
Synonyms:	PHA 665752;PHA-665752/PHA665752;(R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimethyl-4-(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-1H-pyrrol-2-yl)methylene)indolin-2-one;(2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE;(2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE PHA 665752;PHA 665752 (2R)-1-[[5-[(Z)-[5-[[(2,6-Dichlorophenyl)methyl]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrol-3-yl]carbonyl]-2-(1-pyrrolidinylmethyl)pyrrolidine
CBNumber:	CB72448634
Molecular Formula:	C32H34Cl2N4O4S
Formula Weight:	0
MOL File:	477575-56-7.mol

PHA-665752 Property

density :

1.404

storage temp. :

Store at +4°C

Safety

PHA-665752 Chemical Properties,Usage,Production

Biological Activity
Potent, selective and ATP-competitive inhibitor of MET kinase (IC 50 values are 9, 68, 200, 1400, 3000, 3800 and 6000 nM for MET, Ron, Flk-1, c-abl, FGFR1, EGFR and c-src respectively and > 10000 nM for IGF-IR, PDGFR, AURORA2, PKA, PKB α , p38 α , MK2 and MK3). Antitumor agent; inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.

PHA-665752 Preparation Products And Raw materials

Raw materials

Preparation Products

PHA-665752 Suppliers Global( 42)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Wulechem Co., Ltd.	+86-021-31135716 13761914825	+86-021-61624218	wulesian@wulechem.com sales@wulechem.com QQ 409132824	CHINA	271	58
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078,021-50426030	86-021-50426522,50426273	sales@jingyan-chemical.com	CHINA	10108	60
China DongFan Chemical Co.,LTD	86-0571-85151182	86-0571-85151182	sales@dongfan-chem.com	CHINA	5718	66
Jinan Trio PharmaTech Co., Ltd.	+86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;	+86 (531) 55696010 QQ981200479	sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)	CHINA	1779	62
ShangHai Biochempartner Co.,Ltd	+86 13818785766，400-021-9906		gaoqing@biochempartner.com	CHINA	1167	62
T&W GROUP	+86-21-61551611, 61551413, 61551420, 61551610	+86-21-50676805	contact@trustwe.com	CHINA	13395	58
Shanghai civi chemical technology co.,Ltd	86-21-34053660；34053661	86-21-34053661	sale@labgogo.com	CHINA	9958	52

477575-56-7(PHA-665752)Related Search:

Bortezomib Tivantinib (ARQ 197) SU 11274 Veliparib (ABT-888) 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine Olaparib PHA-665752 R)-N-METHYL-2-PYRROLIDIN-1-YLMETHYL-PYRROLIDINE p-(ethylsulfonyl)-anilin 1-(Cloromethyl)-4,5-dihydro-1H-imidazole hydrochloride SU 5416 (R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine

(2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE 477575-56-7 PHA 665752 C32H34Cl2N4O4S (2R)-1-[[5-[(Z)-[5-[[(2,6-DICHLOROPHENYL)METHYL]SULFONYL]-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE]METHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL]CARBONYL]-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE PHA 665752 PHA-665752/PHA665752 (R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimethyl-4-(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-1H-pyrrol-2-yl)methylene)indolin-2-one PHA 665752 (2R)-1-[[5-[(Z)-[5-[[(2,6-Dichlorophenyl)methyl]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrol-3-yl]carbonyl]-2-(1-pyrrolidinylmethyl)pyrrolidine