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CAS No. | 425386-60-3 |
Chemical Name: | Semagacestat |
Synonyms: | LY450139;semagacestat;Unii-3yn0602W4w;Semagacestat/LY-450139;LY450139(Semagacestat);N-benzyl-4-MethylcyclohexanaMine;2-hydroxy-3-Methyl-N-[(1S)-1-Methyl-2-oxo-2-[[(1S)-2;5-tetrahydro-3-Methyl-2-oxo-1H-3-benzazepin-1-yl]aMino]ethyl]-;(2S)-2-hydroxy-3-Methyl-N-[(1S)-1-{[(1S)-3-Methyl-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepin-1-yl]carbaMoyl}ethyl]butanaMide;(2S)-2-HYDROXY-3-METHYL-N-[(2S)-1-{[(1S)-3-METHYL-2-OXO-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-1-YL]AMINO}-1-OXOPROPAN-2-YL]BUTANAMIDE |
CBNumber: | CB71511579 |
Molecular Formula: | C19H27N3O4 |
Formula Weight: | 361.44 |
MOL File: | 425386-60-3.mol |
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Semagacestat Chemical Properties,Usage,Production |
Chemical Properties
White Solid |
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Usage
Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis o
f Alzheimer's disease (AD). |
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Semagacestat Preparation Products And Raw materials |
Raw materials
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Preparation Products
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Semagacestat Suppliers Global( 45)Suppliers |
Supplier | Tel | Fax | Email | Country | ProdList | Advantage |
J & K SCIENTIFIC LTD.
| -- | -- | jkinfo@jkchemical.com;market3@jkchemical.com | CHINA |
96847
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76
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ChemFuture PharmaTech (Jiangsu) Ltd
| 86 510 85386188 ;86 510 85386988-8037 | 86 510 85220778 | Sales@chemfuture.com | CHINA |
784
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65
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Chembest Research Laboratories Limited
| +86(0)21-20908456 | +86(0)21-58180499 | sales@biochembest.com | CHINA |
6000
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61
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Shijiazhuang Sdyano Fine Chemical Co., Ltd.
| +86-311-89250318 | 4000311741 | master@sjzsdyn.com | CHINA |
4980
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65
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Pure Chemistry Scientific Inc.
| 001-857-928-2050 or 1-888-588-9418 | 001-617-206-9595 | sales@chemreagents.com | USA |
9949
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62
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Chemfun Medical Technology(Shanghai) Co., Ltd.
| 021-67220633 & 021-37212706 | +86-21-67220638 | chemfun@chemfun.net | CHINA |
21915
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59
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Shanghai Longsheng chemical Co.,Ltd.
| 0086-21-58099637,58099652,58099650,58099609 To 8017,8068; 13585536065 | 0086-21-33191781 | sales@shlschem.com; bin.wu@shlschem.com;xianjun.hong@shlschem.com | CHINA |
9850
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59
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Chemsky(shanghai)International Co.,Ltd.
| 021-50135380 | | shchemsky@sina.com | CHINA |
32553
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50
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Jinan Trio PharmaTech Co., Ltd.
| +86 (531) 88811793;+86 (531) 88811783;+(0)18854807083; | +86 (531) 55696010 QQ981200479 | sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market) | CHINA |
1779
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62
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ShangHai Biochempartner Co.,Ltd
| +86 13818785766,400-021-9906 | | gaoqing@biochempartner.com | CHINA |
1167
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62
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425386-60-3(Semagacestat)Related Search: |
Thiophanate-methyl
3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one
1-amino-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
4,5-DIHYDRO-1H-BENZO[D]AZEPIN-2(3H)-ONE
2H-3-BENZAZEPIN-2-ONE,1-AMINO-1,3,4,5-TETRAHYDRO-3-METHYL-,(1S)-
1H-3-BENZAZEPIN-1-AMINE, 2,3,4,5-TETRAHYDRO-3-METHYL-
1H-3-BENZAZEPIN-1-AMINE, 2,3,4,5-TETRAHYDRO-
Semagacestat
CHLOROPHOSPHONAZO III
Glycolic acid
Hydroxy silicone oil
Methylparaben
Methyl acrylate
Methyl bromide
10-Hydroxycamptothecin
PENICILLIN V
HYDROXYAPATITE TYPE I
p-Hydroxybenzaldehyde
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(2S)-2-HYDROXY-3-METHYL-N-[(2S)-1-{[(1S)-3-METHYL-2-OXO-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-1-YL]AMINO}-1-OXOPROPAN-2-YL]BUTANAMIDE
425386-60-3
semagacestat
Butanamide, 2-hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5- tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]-, (2S)-
(2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide
Semagacestat/LY-450139
Unii-3yn0602W4w
LY450139(Semagacestat)
LY450139
2-hydroxy-3-Methyl-N-[(1S)-1-Methyl-2-oxo-2-[[(1S)-2
5-tetrahydro-3-Methyl-2-oxo-1H-3-benzazepin-1-yl]aMino]ethyl]-
N-benzyl-4-MethylcyclohexanaMine
(2S)-2-hydroxy-3-Methyl-N-[(1S)-1-{[(1S)-3-Methyl-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepin-1-yl]carbaMoyl}ethyl]butanaMide
Inhibitor
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