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CAS No. | 300815-41-2 |
Chemical Name: | RS 102895 |
Synonyms: | RS 102895 HYDROCHLORIDE;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one;1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride;1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE |
CBNumber: | CB6504368 |
Molecular Formula: | C21H21F3N2O2.ClH |
Formula Weight: | 426.864 |
MOL File: | 300815-41-2.mol |
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RS 102895 Property |
density : |
1.33±0.1 g/cm3 (20 ºC 760 Torr) |
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storage temp. : |
Desiccate at RT |
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solubility : |
DMSO: 18 mg/mL, clear, colorless
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RS 102895 Chemical Properties,Usage,Production |
Biological Activity
CCR2-selective chemokine receptor antagonist (IC 50 values are 0.36 and 17.8 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC 50 values of 32 nM and 1.7 μ M respectively. Also inhibits α 1A , α 1D and 5-HT 1A receptors. |
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RS 102895 Preparation Products And Raw materials |
Raw materials
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Preparation Products
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RS 102895 Suppliers Global( 20)Suppliers |
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300815-41-2(RS 102895)Related Search: |
4-(2-AMINOPHENYL)-1-PHENETHYLPIPERIDINE
4-(O-AMINO-PHENYL) PIPERIDINE HYDROCHLORIDE
RS 102895
1-Phenethyl-4-phenyl-4-piperidinol
SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE
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300815-41-2
1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE
RS 102895 HYDROCHLORIDE
1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one
C21H21F3N2O2HCl
Cytokine signaling
1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride
RS 102895 CCR2-selective chemokine receptor antagonist.
1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride
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