Caffeic acid

Caffeic acid Property

mp : 211-213 °C (dec.)(lit.) storage temp. : Store at RT. solubility : ethanol: 50 mg/mL form : powder color : yellow to tan Water Solubility : soluble in hot water Merck : 14,1635 BRN : 2210883 Stability:: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases. CAS DataBase Reference: 331-39-5(CAS DataBase Reference) NIST Chemistry Reference: Cinnamic acid, 3,4-dihydroxy-(331-39-5) EPA Substance Registry System: 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-(331-39-5)

Safety

Hazard Codes : Xn,Xi Risk Statements : 36/37/38-40-63-68 Safety Statements : 26-36/37/39-36 WGK Germany : 3 RTECS : GD8950000 Hazard Note : Irritant HS Code : 29182990 Hazardous Substances Data: 331-39-5(Hazardous Substances Data)

Caffeic acid Chemical Properties,Usage,Production

Chemical Properties Light yellow to greenish-yellow powder Usage antineoplastic, PGE2 synthase inhibitor, PK inhibitor Usage Caffeic Acid is a constituent of plants, probably occurs in plants only in conjugated forms. Caffeic acid is found in all plants because it is a key intermediate in the biosynthesis of lignin, one of the principal sources of biomass. Caffeic acid is one of the main natural phenols in argan oi. General Description Yellow prisms or plates (from chloroform or ligroin) or pale yellow granules. Alkaline solutions turn from yellow to orange. Air & Water Reactions Insoluble in water. Reactivity Profile Caffeic acid is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Caffeic acid to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions. Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition Caffeic acid emits acrid smoke and fumes. Fire Hazard Flash point data for Caffeic acid are not available; however, Caffeic acid is probably combustible.

Caffeic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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