L-655,708

CAS No.	130477-52-0
Chemical Name:	L-655,708
Synonyms:	MSD;L-655,708;ETHYL (S)-11,12,13,13A-TETRAHYDRO-7-METHOXY-9-OXO-9H-IMIDAZO[1,5-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINE-1-CARBOXYLATE;Ethyl (S)-11,12,13,13a-Tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylate;11,12,13,13a-Tetrahydro-7-methoxy-9-oxo-9H-imidazo[1.5-a]pyrrolo[2.1-c][1.4]benzodiazepine-1-carboxylicacidethylester;11,12,13,13A-TETRAHYDRO-7-METHOXY-9-OXO-9H-IMIDAZO[1,5-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINE-1-CARBOXYLIC ACID, ETHYL ESTER;9H-IMidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, 11,12,13,13a-tetrahydro-7-Methoxy-9-oxo-, ethyl ester, (13aS)-;9H-IMidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, 11,12,13,13a-tetrahydro-7-Methoxy-9-oxo-, ethyl ester, (13aS)- (011-14426_500Mg)
CBNumber:	CB4345633
Molecular Formula:	C18H19N3O4
Formula Weight:	341.36
MOL File:	130477-52-0.mol

L-655,708 Property

storage temp. :

Desiccate at +4°C

solubility :

DMSO: 6 mg/mL

form :

powder

Safety

WGK Germany :

L-655,708 Chemical Properties,Usage,Production

Biological Activity
Potent, selective inverse agonist for the benzodiazepine site of GABA A receptors containing the α 5 subunit (K i = 0.45 nM). Displays 50-100-fold selectivity over GABA A receptors containing α 1, α 2, α 3 or α 6 subunits in combination with β 3 and γ 2. Enhances LTP in? a mouse hippocampal slice model and increases spatial learning, without displaying proconvulsant activity.

L-655,708 Preparation Products And Raw materials

Raw materials

Preparation Products

L-655,708 Suppliers Global( 12)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
Tianjin SPHINX SCIENTIFIC LAB.	022-66211289-808(CHINA)；	022-66211370(CHINA);	sales1@sphinxscientificlab.com	CHINA	1918	62
MedChemexpress LLC	609-228-6898	609-228-5909	sales@medchemexpress.cn	USA	4935	58
EMMX Biotechnology LLC	888-539-0666	888-539-0666	info@emmx.com	USA	8489	60

130477-52-0(L-655,708)Related Search:

[3H]-L-655,708,L-655,708, [1',1',1'-3H] 2-(1H-IMIDAZOL-1-YL)BENZENECARBOXAMIDE 2-IMIDAZOL-1-YL-BENZALDEHYDE 4-(5-METHYL-1H-IMIDAZOL-1-YL)PHENOL 4-(1H-IMIDAZOL-4-YL)-BUTYLAMINE 1-[2-(1H-IMIDAZOL-1-YL)PHENYL]METHANAMINE L-655,708

ETHYL (S)-11,12,13,13A-TETRAHYDRO-7-METHOXY-9-OXO-9H-IMIDAZO[1,5-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINE-1-CARBOXYLATE L-655,708 130477-52-0 11,12,13,13A-TETRAHYDRO-7-METHOXY-9-OXO-9H-IMIDAZO[1,5-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINE-1-CARBOXYLIC ACID, ETHYL ESTER 11,12,13,13a-Tetrahydro-7-methoxy-9-oxo-9H-imidazo[1.5-a]pyrrolo[2.1-c][1.4]benzodiazepine-1-carboxylicacidethylester Ethyl (S)-11,12,13,13a-Tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylate GABA/Glycine receptor MSD 9H-IMidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, 11,12,13,13a-tetrahydro-7-Methoxy-9-oxo-, ethyl ester, (13aS)- (011-14426_500Mg) 9H-IMidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, 11,12,13,13a-tetrahydro-7-Methoxy-9-oxo-, ethyl ester, (13aS)-