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SL 327

CAS No.305350-87-2
Chemical Name:SL 327
Synonyms:SL 327;(Z)-3-amino-3-(4-aminophenylthio)-2-(2-(trifluoromethyl)phenyl)acrylonitrile;α-[amino-(4-aminophenylthio)methylene)-2-(trifluoromethyl)phenylacetonitrile;α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile;a-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile;ALPHA-[AMINO-(4-AMINOPHENYLTHIO)METHYLENE)-2-(TRIFLUOROMETHYL)PHENYLACETONITRILE;ALPHA-[AMINO[(4-AMINOPHENYL)THIO]METHYLENE]-2-(TRIFLUOROMETHYL)BENZENEACETONITRILE;(2Z)-3-amino-3-[(4-aminophenyl)sulfanyl]-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile;SL 327 alpha-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile;Z-AND E-ALPHA-(AMINO-((4-AMINOPHENYL)THIO)METHYLENE)-2-(TRIFLUOROMETHYL)BENZENEACETONITRILE
CBNumber:CB4168773
Molecular Formula:C16H12F3N3S
Formula Weight:335.35
MOL File:305350-87-2.mol
SL 327 Property
mp : 127-128.2 °C
density : 1.40
storage temp. : 2-8°C
solubility : DMSO: 32 mg/mL
form : solid
color : white
Safety
WGK Germany : 3

SL 327 Chemical Properties,Usage,Production

Biological Activity
Selective inhibitor of MEK1 and MEK2 (IC 50 values are 0.18 and 0.22 μ M respectively); blocks hippocampal LTP in vitro . Brain penetrant in vivo , blocking fear conditioning and learning in rats, and producing neuroprotection in mice, following systemic administration.
SL 327 Preparation Products And Raw materials
Raw materials
Preparation Products
SL 327 Suppliers      Global( 28)Suppliers     
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3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Chembest Research Laboratories Limited +86(0)21-20908456+86(0)21-58180499sales@biochembest.comCHINA 6000 61
Ascent Scientific 44011798299884402030 700 369customerservice@ascentscientific.co.ukUNITED KINGDOM 282 60
China DongFan Chemical Co.,LTD 86-0571-8515118286-0571-85151182sales@dongfan-chem.comCHINA 5718 66
Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;+86 (531) 55696010 QQ981200479sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)CHINA 1779 62
BOC Sciences 1-631-504-60931-631-614-7828sales@bocsci.comUSA 9972 65
NCE Biomedical Co.,Ltd. 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988+86-27-87599188sales@ncebiomed.comCHINA 1503 55
Shanghai Haoyuan Chemexpress Co., Ltd 86-21-5899859086-21-53700326, 86-21-58998590sales@chemexpress.cnCHINA 10011 61
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333021-50323701sale@aladdin-e.comCHINA 24330 65
MedChemexpress LLC 609-228-6898609-228-5909sales@medchemexpress.cnUSA 4935 58
 
305350-87-2(SL 327)Related Search:
AS703026 Binimetinib (MEK162, ARRY-162, ARRY-438162) AZD 6244 Ridaforolimus (Deforolimus, MK-8669) BIX 02189 PD 0325901 Benzeneacetonitrile 2-(TRIFLUOROMETHYL)PHENYLACETONITRILE SL 327
ALPHA-[AMINO[(4-AMINOPHENYL)THIO]METHYLENE]-2-(TRIFLUOROMETHYL)BENZENEACETONITRILE ALPHA-[AMINO-(4-AMINOPHENYLTHIO)METHYLENE)-2-(TRIFLUOROMETHYL)PHENYLACETONITRILE BioChemical Cell Biology Cell Signaling and Neuroscience 305350-87-2 SL 327 Kinase/Phosphatase Biology Mitogen-Activated Protein Kinase Kinase (MAPKK) Serine/Threonine Kinase Inhibitors Z-EPSILON-T E-ALPHA-(AMINO-((4-AMINOPHENYL)THIO)METHYLENE)-2-(TRIFLUOROMETHYL)BENZENEACETONITRILE Z-AND E-ALPHA-(AMINO-((4-AMINOPHENYL)THIO)METHYLENE)-2-(TRIFLUOROMETHYL)BENZENEACETONITRILE a-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile α-[amino-(4-aminophenylthio)methylene)-2-(trifluoromethyl)phenylacetonitrile Protein Kinase Signalling α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile C16H12F3O3S (2Z)-3-amino-3-[(4-aminophenyl)sulfanyl]-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile (Z)-3-amino-3-(4-aminophenylthio)-2-(2-(trifluoromethyl)phenyl)acrylonitrile alpha-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile SL 327 SL 327 alpha-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile
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