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TPCA-1

CAS No.507475-17-4
Chemical Name:TPCA-1
Synonyms:TPCA-1;GW683965;GW683965A;TPCA-1(TPCA 1);TPCA-1 IKK-2 Inhibitor IV;5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide;2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide;3-ThiophenecarboxaMide, 2-[(aMinocarbonyl)aMino]-5-(4-fluorophenyl)-;5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide TPCA-1
CBNumber:CB41073580
Molecular Formula:C12H10FN3O2S
Formula Weight:279.294
MOL File:507475-17-4.mol
TPCA-1 Property
density : 1.490
storage temp. : 2-8°C
Safety
Hazard Codes : Xn
Risk Statements : 22-36
Safety Statements : 26

TPCA-1 Chemical Properties,Usage,Production

Biological Activity
Potent, selective inhibitor of I κ B kinase-2 (IKK-2) (IC 50 = 17.9 nM) that displays > 22-fold selectivity over IKK-1 and > 550-fold selectivity over other kinases and enzymes. Inhibits production of pro-inflammatory cytokines in vitro and in vivo and inhibits NF- κ B nuclear localisation. Reduces the severity and onset of collagen-induced arthritis; anti-inflammatory.
TPCA-1 Preparation Products And Raw materials
Raw materials
Preparation Products
TPCA-1 Suppliers      Global( 27)Suppliers     
SupplierTelFaxEmailCountryProdListAdvantage
Yangzhou Siyu Chemical Co.,Ltd. 0514-87325867;133581261960086-514-87325867sales@siyuchem.comCHINA 1652 55
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Chembest Research Laboratories Limited +86(0)21-20908456+86(0)21-58180499sales@biochembest.comCHINA 6000 61
SHANGHAI SUN-SHINE BIO-TECHNOLOGY CO,,LIMITED 0086-27-5925 3327; QQ:401996140086-27-5925 3326sales@sun-shinechem.comCHINA 302 64
Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811793;+86 (531) 88811783;+(0)18854807083;+86 (531) 55696010 QQ981200479sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)CHINA 1779 62
Wuhan Sunrise Technology Development Co., Ltd. +86 (27) 8331-4682 / +86 13554138826+86 (27) 8331-4682whsrtech@vip.163.com,whsrtech@whsrtech.comCHINA 269 62
Hangzhou Sage Chemical Co., Ltd. 0571-86818502Pls mail us for more information!info@sagechem.comCHINA 10286 58
NCE Biomedical Co.,Ltd. 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988+86-27-87599188sales@ncebiomed.comCHINA 1503 55
Shanghai Haoyuan Chemexpress Co., Ltd 86-21-5899859086-21-53700326, 86-21-58998590sales@chemexpress.cnCHINA 10011 61
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333021-50323701sale@aladdin-e.comCHINA 24330 65
 
507475-17-4(TPCA-1)Related Search:
BAY 11-7082 IKK 16 AZD 6244 MG-132 Trametinib (GSK1120212) IKK Inhibitor III, BMS-345541 TPCA-1
507475-17-4 TPCA-1 2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide TPCA-1(TPCA 1) 3-ThiophenecarboxaMide, 2-[(aMinocarbonyl)aMino]-5-(4-fluorophenyl)- 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide TPCA-1 TPCA-1 IKK-2 Inhibitor IV GW683965 GW683965A
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