|
|
| CAS No. | 37854-59-4 |
| Chemical Name: | RO 08-2750 |
| Synonyms: | RO 08-2750;2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde |
| CBNumber: | CB3844689 |
| Molecular Formula: | C13H10N4O3 |
| Formula Weight: | 270.247 |
| MOL File: | 37854-59-4.mol |
|
|
|
|
| RO 08-2750 Property |
| storage temp. : |
Store at -20°C |
|
|
RO 08-2750 Chemical Properties,Usage,Production |
Biological Activity
Non-peptide inhibitor of NGF that binds the NGF dimer (K D ~ 1 μ M) possibly causing a conformational change. Inhibits binding selectively to p75 NTR at submicromolar concentrations and to both p75 NTR and TrkA at higher concentrations (> 5 μ M). Prevents NGF-induced apoptosis in SK-N-MC cells. |
|
|
| RO 08-2750 Preparation Products And Raw materials |
Raw materials
|
Preparation Products
|
| RO 08-2750 Suppliers Global( 4)Suppliers |
|
|
|
|
|