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CAS No. | 83852-56-6 |
Chemical Name: | CHRYSOMYCIN B |
Synonyms: | B,ChrysoMycin;ChrysoMycin M, VirenoMycin M, Albacarcin M;4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one;6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl- (9CI) |
CBNumber: | CB3503294 |
Molecular Formula: | C27H28O9 |
Formula Weight: | 496.509 |
MOL File: | 83852-56-6.mol |
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CHRYSOMYCIN B Property |
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solubility : |
DMF: soluble
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CHRYSOMYCIN B Chemical Properties,Usage,Production |
Usage
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumour actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumour active and an inhibitor of the catalytic activity of human topoisomerase II. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated crosslinkers of DNA to histones. |
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Usage
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumor active and an inhibitor of the catalytic activity of human topoisomerase II. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated cross-linkers of DNA to histones. |
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CHRYSOMYCIN B Preparation Products And Raw materials |
Raw materials
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Preparation Products
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CHRYSOMYCIN B Suppliers Global( 9)Suppliers |
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83852-56-6
A - KAntibiotics
Antibacterial
Antibiotics A to
Antibiotics A-FAntibiotics
Antibiotics by Application
Antineoplastic and Immunosuppressive AntibioticsAntibiotics
Inhibits an EnzymeEnzyme Inhibitors by Enzyme
Mechanism of Action
R to
Spectrum of Activity
Topoisomerase II
4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one
B,ChrysoMycin
ChrysoMycin M, VirenoMycin M, Albacarcin M
6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl- (9CI)
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