3,3',4',5,7-Pentahydroxyflavone

CAS No.	117-39-5
Chemical Name:	3,3',4',5,7-Pentahydroxyflavone
Synonyms:	MELETIN;natural;QUERTINE;QUERCETOL;QUERCITIN;QUERCETIN;kvercetin;Sophretin;QUERCETINE;SOPHORETIN
CBNumber:	CB3230765
Molecular Formula:	C15H10O7
Formula Weight:	302.24
MOL File:	117-39-5.mol

3,3',4',5,7-Pentahydroxyflavone Property

mp :

314-317°C

storage temp. :

Store at 0-5°C

Water Solubility :

<0.1 g/100 mL at 21 ºC

Merck :

13,8122

CAS DataBase Reference:

117-39-5(CAS DataBase Reference)

EPA Substance Registry System:

4H-1-Benzopyran- 4-one, 2-(3,4-dihydroxyphenyl)-3, 5,7-trihydroxy-(117-39-5)

Safety

Hazard Codes :

T,Xi

Risk Statements :

25-36/37/38

Safety Statements :

45-36-26

RIDADR :

2811

RTECS :

LK8750000

HazardClass :

6.1(b)

PackingGroup :

III

Hazardous Substances Data:

117-39-5(Hazardous Substances Data)

3,3',4',5,7-Pentahydroxyflavone Chemical Properties,Usage,Production

Chemical Properties
Yellow to green yellow crystalline powde

General Description
Yellow needles or yellow powder. Converts to anhydrous form at 203-207°F. Alcoholic solutions taste very bitter.

Air & Water Reactions
Sensitive to exposure to air and light. Insoluble in water.

Reactivity Profile
3,3',4',5,7-Pentahydroxyflavone is a strong antioxidant and a metal chelator. Promotes the formation of nitrosamines .

Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition 3,3',4',5,7-Pentahydroxyflavone emits acrid smoke and irritating fumes.

Fire Hazard
Flash point data for 3,3',4',5,7-Pentahydroxyflavone are not available; however, 3,3',4',5,7-Pentahydroxyflavone is probably combustible.

Biological Activity
Anti-tumor agent; induces apoptosis and inhibits synthesis of heat shock proteins. Inhibits many enzyme systems including tyrosine protein kinase, phospholipase A 2 , phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Can also activate Ca 2+ and K + channels and behaves as an agonist at estrogen (GPR30) receptors.

3,3',4',5,7-Pentahydroxyflavone Preparation Products And Raw materials

Raw materials
Anise oil ISOQUERCETIN(P) Rutin Hyperoside 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-benzopyran-4-one

Preparation Products

3,3',4',5,7-Pentahydroxyflavone Suppliers Global( 183)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Shaanxi Huike Botanical Development Co., Ltd	+86-29-62663046;+86-18706899381	+86-29-82606529	market@huikes.com	CHINA	61	62
Chengdu Ai Keda Chemical Technology Co., Ltd.	4008-755-333 ; 028-86676798 ; 028-86757656	028-86757656	aikeshiji@163.com	CHINA	9909	55
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
Nanjing Elegant Nutraceuticals Co., Ltd	0086-25-83241153, 83241163	0086-25-83241173	sales@elegantnutri.com	CHINA	50	55
INTATRADE GmbH	+49 3493/605464	+49 3493/605470	sales@intatrade.de	GERMANY	3590	66
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
future industrial shanghai co., ltd	021-61552785，400-0066-400	021-55660885	sales@jonln.com	CHINA	2037	65
Arden pharmaceutical &chemical Co., Ltd	+86-(0)533-3595900 13793319233	+86-(0)533-3595900	info@chems.com.cn	CHINA	672	61
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
ShangHai DEMO Chemical Co.,Ltd	0086-21-50182335 400-021-7337	0086-21-50182339	sales@demochem.com; export1@demochem.com	CHINA	3120	57

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117-39-5 2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE 3,3',4',5,6-PENTA-HYDROXY-FLAVONE 3,3',4',5,7-PENTAHYDROXYFLAVONE AKOS NCG1-0081 MELETIN FLAVIN MELETIN LABOTEST-BB LT00455149 CI NO 75670 XANTHAURINE QUERCETINE QUERTINE QUERCETOL QUERCITIN QUERCETIN SOPHORETIN Flavonoids 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on 3,5,7,3’,4’-pentahydroxyflavone 3’,4’,5,7-tetrahydroxyflavan-3-ol c.i.naturalyellow10 cinaturalyellow10 cyanidelonon1522 kvercetin natural naturalyellow10 nci-c60106 t-gelbbzw.grun1 3,3,4,5,7-Pentahydroxyflavone (pract) Quercetin anhydrous QUERCETIN FROM GINKGO BILOBA LEAF PLANT EXTRACT 99+%(HPLC) QUERCETIN 98+% NATURAL STANDARD 15042-74-1 Sophorefin 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy- Pharmaceutical Raw Materials QUERCETIN hplc Miscellaneous Natural Products 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one QUERCETIN DERIVATIVES KIT QUERCETIN WITH HPLC Functional Products Natural Plant Extract 3,5,7-trihydroxy-,dihydrate 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)- 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, 3,3μ,4μ,5,6-Pentahydroxyflavone Caspases/Apoptosis 6151—21一3 Quercetin (Ethanol Solution) [for Spray] Cyanidenolon 1522 Sophorecin 3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one QUERCETAGETINIDIN CHLORIDE(SH) reference substance Quercetin,2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, 3,3′,4′,5,6-Pentahydroxyflavone 3,3',4',5,7-Pentahyd Rhamnose,Lightyellow Sophora Extracts Quercetin(Sophoretin)