(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide

CAS No.	698387-09-6
Chemical Name:	(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Synonyms:	neratinib;Unii-jjh94R3pwb;PB272(neratinib);HKI-272 Neratinib;Neratinib(HKI-272);N-(4-(3-Chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide;(E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide;(2E)-N-[4-[[3-chloro-4-(2-pyridinylMethoxy)phenyl]aMino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(diMethylaMino)-2-butenaMide;(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-emide;2-ButenaMide,N-[4-[[3-chloro-4-(2-pyridinylMethoxy)phenyl]aMino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(diMethylaMino)-,(2E)-
CBNumber:	CB2855051
Molecular Formula:	C30H29ClN6O3
Formula Weight:	557.04266
MOL File:	698387-09-6.mol

(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide Property

density :

1.33

Safety

(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide Chemical Properties,Usage,Production

Usage
Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM, respectively.

Usage
An oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer. Antitumor agent

(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide Preparation Products And Raw materials

Raw materials

Preparation Products

(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide Suppliers Global( 103)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Jiangsu Allyrise Pharmaceutical Co., LTD	+86-523-86818697 18652728585	+86-523-86818697	sales@allyrise.com	CHINA	928	60
Jinan XuanDe Chemical Co., Ltd.	0531-88803958 13685313757 QQ:2098388591 123732808	0531-82777287	18853169188@163.com	CHINA	154	58
Longdo (Shanghai) Biotechnology Co., Ltd.	15921477627	-	263302768@qq.com	CHINA	19	58
Changzhou Fang Nan Medical Technology Co., Ltd.	0519-85283269 0519-85283268	0519-85283269	sales@alnovapharm.com	CHINA	101	55
Intelligence Pharm Science(Shanghai) Co., Ltd.	021-57898186	021-37699262	sales@intelligencepharm.com	CHINA	450	55
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
ShangHai DEMO Chemical Co.,Ltd	0086-21-50182335 400-021-7337	0086-21-50182339	sales@demochem.com; export1@demochem.com	CHINA	3120	57
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078,021-50426030	86-021-50426522,50426273	sales@jingyan-chemical.com	CHINA	10108	60

698387-09-6((2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide)Related Search:

Lenvatinib (E7080) Tofacitinib (CP-690550,Tasocitinib) Axitinib Paclitaxel Gefitinib Bortezomib ABT 263 Ibrutinib 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine BIBW 2992 Lapatinib Ditosylate Ethoxyquin 4-(pyridin-2-ylmethoxy)aniline (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide AKOS B033273

(2e)-n-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide 698387-09-6 neratinib (E)-N-[4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide C30H29ClN6O3 N-(4-(3-Chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide Unii-jjh94R3pwb Neratinib(HKI-272) (2E)-N-[4-[[3-chloro-4-(2-pyridinylMethoxy)phenyl]aMino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(diMethylaMino)-2-butenaMide (2e)-n-(4-((3-chloro-4-((pyridin-2-yl)Methoxy)phenyl)aMino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(diMethylaMino)but-2-enaMide neratinib Antineoplastic Anti-cancer & immunity 2-ButenaMide,N-[4-[[3-chloro-4-(2-pyridinylMethoxy)phenyl]aMino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(diMethylaMino)-,(2E)- HKI-272 Neratinib Neratinib HKI-272 (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide Neratinib (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-emide PB272(neratinib)