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CAS No. | 132861-87-1 |
Chemical Name: | (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE |
Synonyms: | PD 81,723;4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine;(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone;(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone;(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE;Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-;(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone |
CBNumber: | CB2484082 |
Molecular Formula: | C14H12F3NOS |
Formula Weight: | 299.31 |
MOL File: | 132861-87-1.mol |
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(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Property |
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solubility : |
DMSO: ~13 mg/mL
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(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Chemical Properties,Usage,Production |
Biological Activity
Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo . |
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(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Preparation Products And Raw materials |
Raw materials
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Preparation Products
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(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Suppliers Global( 13)Suppliers |
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132861-87-1
(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
PD 81,723
C14H12F3NOS
Adenosine receptor
(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone
(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone
4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine
Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-
(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone
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