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| CAS No. | 366017-09-6 |
| Chemical Name: | Mubritinib |
| Synonyms: | TAK 165;MUBRITINIB;Mubritinib(TAK 165);(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;Mubritinib 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole Mubritinib (TAK 165) |
| CBNumber: | CB21011746 |
| Molecular Formula: | C25H23F3N4O2 |
| Formula Weight: | 468.47 |
| MOL File: | 366017-09-6.mol |
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| Mubritinib Property |
| storage temp. : |
Store at +4°C |
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Mubritinib Chemical Properties,Usage,Production |
Biological Activity
Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC 50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC 50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo . |
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| Mubritinib Preparation Products And Raw materials |
Raw materials
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Preparation Products
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| Mubritinib Suppliers Global( 52)Suppliers |
| Supplier | Tel | Fax | Email | Country | ProdList | Advantage |
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3B Pharmachem (Wuhan) International Co.,Ltd.
| 86-21-50328103 * 801、802、803、804 Mobile:18930552037 | 86-21-50328109 | 67055399@qq.com | CHINA |
15983
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69
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Chembest Research Laboratories Limited
| +86(0)21-20908456 | +86(0)21-58180499 | sales@biochembest.com | CHINA |
6000
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61
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Chemfun Medical Technology(Shanghai) Co., Ltd.
| 021-67220633 & 021-37212706 | +86-21-67220638 | chemfun@chemfun.net | CHINA |
21915
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59
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LGM Pharma
| 1-(800)-881-8210 | 615-250-9817 | inquiries@lgmpharma.com | USA |
1972
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70
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Shanghai Longsheng chemical Co.,Ltd.
| 0086-21-58099637,58099652,58099650,58099609 To 8017,8068; 13585536065 | 0086-21-33191781 | sales@shlschem.com; bin.wu@shlschem.com；xianjun.hong@shlschem.com | CHINA |
9850
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59
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China DongFan Chemical Co.,LTD
| 86-0571-85151182 | 86-0571-85151182 | sales@dongfan-chem.com | CHINA |
5718
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66
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Jinan Trio PharmaTech Co., Ltd.
| +86 (531) 88811793；+86 (531) 88811783;+(0)18854807083; | +86 (531) 55696010 QQ981200479 | sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market) | CHINA |
1779
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62
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BOC Sciences
| 1-631-504-6093 | 1-631-614-7828 | sales@bocsci.com | USA |
9972
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65
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NCE Biomedical Co.,Ltd.
| 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988 | +86-27-87599188 | sales@ncebiomed.com | CHINA |
1503
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55
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（CSR Factory）China Skyrun Industrial CO.,ltd
| info@chinaskyrun.com | manager@chinaskyrun.com | sales@chinaskyrun.com | CHINA |
12226
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58
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366017-09-6
MUBRITINIB
C25H23F3N4O2
1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole
TAK 165
Mubritinib(TAK 165)
(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole
1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole Mubritinib (TAK 165)
Mubritinib 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole
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