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SEMUSTINE

CAS No.13909-09-6
Chemical Name:SEMUSTINE
Synonyms:Me-CCNU;icig1110;Semustin;SEMUSTINE;ICIG 1110;NSC 95441;nsc-95441;trans-ure;NCI-C04955;Aids126009
CBNumber:CB1173336
Molecular Formula:C10H18ClN3O2
Formula Weight:247.72
MOL File:13909-09-6.mol
SEMUSTINE Property
Safety
Hazard Codes : T
Risk Statements : 45-46-23/24/25-36/37/38
Safety Statements : 53-22-26-36/37/39-45
RIDADR : 3249
WGK Germany : 3
RTECS : YS5000000
HazardClass : 6.1(a)
PackingGroup : II

SEMUSTINE Chemical Properties,Usage,Production

Usage
Commonly used in pharmacological studies involving: • ;Nutrient-sensitized screening for drugs that shift the energy metabolism from mitchondrial respiration to glycolysis1• ;CEOP regimen with semustine used as induction chemotherapy in patients with lymphoma2• ;Investigations into its use for chemotherapy3,4
Usage
antihyperlipidemic
General Description
Light yellow powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A halogenated and nitrated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Fire Hazard
Flash point data for SEMUSTINE are not available. SEMUSTINE is probably combustible.
SEMUSTINE Preparation Products And Raw materials
Raw materials
Preparation Products
SEMUSTINE Suppliers      Global( 28)Suppliers     
SupplierTelFaxEmailCountryProdListAdvantage
Syntechem Co.,Ltd info@syntechem.com QQ 421151915E-Mail Inquiryinfo@syntechem.comCHINA 13109 57
Dalian Meilun Biotech Co., Ltd. 0411-66771943；0411-667719420411-66771945sales@meilune.comCHINA 5010 58
Shanghai LiuShi Pharmaceutical Technology Co., Ltd. 021-60135539021-38721356shlschemical@hotmail.comCHINA 9967 55
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969020-39119999isunpharm@qq.com, isunpharm@hotmail.comCHINA 4836 55
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979021-34692979info@tsbiochem.comCHINA 8124 58
Sigma-Aldrich 021-61415566 800-819-3336(Tel) 400-620-3333(Mobile)021-61415567orderCN@sial.comCHINA 7506 80
Alfa Chemistry 1-201-478-85341-516-927-0118inquiry@alfa-chemistry.comUSA 9996 60
 
13909-09-6(SEMUSTINE)Related Search:
CIS-4-METHYL-CYCLOHEXYLAMINE HCL Lomustine N-NITROSOMETHYL-2-CHLOROETHYLAMINE 4-Methylcyclohexyl amine trans-4-Methylcyclohexyl amine SEMUSTINE 1-nitroso-1-ethyl-3-methylurea N-NITROSO-N-ETHYLUREA 1-CYCLOHEXYL-3-(2-CHLOROETHYL)UREA 4-METHYLCYCLOHEXYLAMINE HYDROCHLORIDE 1-Methyl-1-nitrosourea 1-(2-chloroethyl)-1-nitrosourea N-CYCLOHEXYLHYDRAZINECARBOXAMIDE 1-(2-Chloroethyl)-3-(4-ethylcyclohexyl)-1-nitrosourea 1,3-diethyl-1-nitrosourea N,N'-dimethylnitrosourea
Nitroso Compounds Nitrogen Compounds Organic Building Blocks N-[2-CHLOROETHYL]-N'-[4-METHYLCYCLOHEXYL]-N-NITROSOUREA SEMUSTINE 13909-09-6 Building Blocks 1-(2-Chloroethyl)-1-([(4-methylcyclohexyl)amino]carbonyl)-2-oxohydrazine 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-ure 1-(2-Chloroethyl)-3-(4-methyl-cyclohexyl)-1-nitrosourea 1-(2-Chloroethyl)-3-(trans-4-methyl-cyclohexyl)-1-nitrosourea ICIG 1110 icig1110 Lomustine, methyl- Me-CCNU Methyl-CCNU methyl-lomustin N-(2-Chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea n-(2-chloroethyl)-n’-(4-methylcyclohexyl)-n-nitroso-ure n-(2-chloroethyl)-n’-(trans-4-methylcyclohexyl)-n-nitrosourea NCI-C04955 NSC 95441 nsc-95441 trans-Methyl-ccnu trans-ure Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso- Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, (E)- Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, trans- Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso- Semustin SEMUSTINE(ME-CCNU) FACT.STANDARD C10H18ClN3O2 N-(4-METHYLCYCLOHEXYL)-N-(2-CHLOROETHYL)-N-NITROSOUREA 1-(2-Chloroethyl)-3-(trans-4-methylcyclohexane)-1-nitrosourea 1-(2-Choroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea Aids126009 Aids-126009 Semustine,N-(2-Chloroethyl)-N′-(4-methylcyclohexyl)-N-nitrosourea Building Blocks Chemical Synthesis Nitrogen Compounds Nitroso Compounds Organic Building Blocks ATROMID
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