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BEZ235 (NVP-BEZ235, Dactolisib)

CAS No.915019-65-7
Chemical Name:BEZ235 (NVP-BEZ235, Dactolisib)
Synonyms:BEZ-235;Dactolisib;NVP-BEZ 235;BEZ235 0.6G;NVP-BEZ235(BEZ235);BEZ235 (NVP-BEZ235);BEZ235 (NVP-BEZ235, Dactolisib);2-Methyl-2-[3-Methyl-2-oxo-8-(3-quinolinyl)-1-iMidazo[4,5-c]quinolinyl]propanenitrile;2-Methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl;2-methyl-2-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl)propanenitrile
CBNumber:CB01872365
Molecular Formula:C30H23N5O
Formula Weight:469.54
MOL File:915019-65-7.mol
BEZ235 (NVP-BEZ235, Dactolisib) Property
mp : 288-289°C
density : 1.299
storage temp. : Refrigerator
Safety

BEZ235 (NVP-BEZ235, Dactolisib) Chemical Properties,Usage,Production

Chemical Properties
Light Beige Solid
Usage
A dual ATP-competitive inhibitor of PI3K and mTOR. p110α, IC50=4 nM; p110β, IC50=75 nM; p110δ, IC50=7 nM; p110γ, IC50=5 nM.
Usage
Inhibitor of phosphatidylinositol 3-kinases, P13K and mTOR.
BEZ235 (NVP-BEZ235, Dactolisib) Preparation Products And Raw materials
Raw materials
Preparation Products
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915019-65-7(BEZ235 (NVP-BEZ235, Dactolisib))Related Search:
Everolimus AZD 6244 MK-2206 2HCl Pictilisib (GDC-0941) Trametinib (GSK1120212) Rapamycin 3,4-DIAMINOQUINOLINE BEZ235 (NVP-BEZ235, Dactolisib) 3-Amino-4-phenylaminopyridine 1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE
915019-65-7 NVP-BEZ 235 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile C30H23N5O 2-methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl)phenyl)propanenitrile BEZ235 0.6G BEZ235 (NVP-BEZ235) 2-methyl-2-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl)propanenitrile 2-Methyl-2-[3-Methyl-2-oxo-8-(3-quinolinyl)-1-iMidazo[4,5-c]quinolinyl]propanenitrile 4-[2,3-Dihydro-3-Methyl-2-oxo-8-(quinolin-3-yl)-1H-iMidazo[4,5-c]quinolin-1-yl]-alpha,alpha-diMethylbenzeneacetonitrile BEZ-235 Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators 4-[2,3-Dihydro-3-Methyl-2-oxo-8-(3-quinolinyl)-1H-iMidazo[4,5-c]quinolin-1-yl]-α,α-diMethyl-benzeneacetonitrile NVP-BEZ235(BEZ235) BEZ235 (NVP-BEZ235, Dactolisib) 2-Methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl api Dactolisib 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile BEZ235(NVP-BEZ235) NVP-BEZ 235 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile Benzeneacetonitrile, 4-[2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-.alpha.,.alpha.-dimethyl-
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