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| CAS-Nr. | 33419-42-0 |
| Bezeichnung: | Etoposid |
| Englisch Name: | Etoposide |
| Synonyma: | Etoposid
epe;epec;e[qr];VP-16;nk171;Etopl;lastet;Eposin;vepesid;Toposar |
| CBNumber: | CB8270005 |
| Summenformel: | C29H32O13 |
| Molgewicht: | 588.56 |
| MOL-Datei: | 33419-42-0.mol |
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| Etoposid physikalisch-chemischer Eigenschaften |
| Schmelzpunkt:: |
236-251 °C(lit.)
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| Brechungsindex: |
-110.5 ° (C=0.6, CHCl3) |
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| storage temp. : |
Store at RT |
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| solubility : |
DMSO: 30 mg/mL
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| EPA chemische Informationen: |
Furo[3',4': 6,7]naphtho[2,3-d]-1,3-dioxol- 6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-. beta.-D-glucopyranosyl]oxy]- 5,8,8a,9-tetrahydro-5-(4- hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-(33419-42-0) |
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Etoposid Chemische Eigenschaften,Einsatz,Produktion Methoden |
Chemische Eigenschaften
White Crystalline Powder |
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Verwenden
An antitumur agent that complexes with topoisomerase II and DNA to enhance double-strand and single strand cleavage of DNA and reversible inhitit religation. Blocks the cell cycle in S-phase and G2-phase of the cell cycle. Induces apoptosis in nor |
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Verwenden
A DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic. |
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R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut. |
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S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren. |
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Biologische Aktivit?t
Topoisomerase II inhibitor (IC 50 = 59.2 μ M). |
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| Etoposid Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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| Etoposid Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 216)Lieferanten |
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Sugars
VP-16
VP-16-213
4’-demethyl-epipodophyllotoxin-beta-d-ethyliden-glucosid
4’-demethylepipodophyllotoxinethylidene-beta-d-glucoside
4’-o-demethyl-1-o-(4,6-o-ethylidene-beta-d-glucopyranosyl)epipodophyllotoxin
9-((4,6-o-ethylidine-beta-d-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydro
demethyl-epipodophyllotoxinethylideneglucoside
e[qr]
epe
epec
epipodophyllotoxin,4’-demethyl-,4,6-o-ethylidene-beta-d-glucopyranoside
epipodophyllotoxin,4’-demethyl-,9-(4,6-o-ethylidene-beta-d-glucopyranoside)
lastet
nk171
nsc141540
nsc-141540
vepesid
vepesidj
xy-3,4-dimethyloxyphenyl)furo(3’,4’’:6,7)naptho-(2,3-d)-1,3-dioxol-6(5ah)-on
ETOPOSIDE 4-O-B-D-GALACTOPYRANOSIDE
ETOPOSIDE
33419-42-0
BioChemical
Antibiotics
Antibiotics A-F
Antibiotics A to Z
[5R-[5A,5AB,8AA,9B(R*)]]-9-[(4,6-O-ETHYLIDENE-BETA-D-GLUCOPYRANSOYL)OXY]-5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)FURO[3',4':6,7]NAPTHO[2,3-D]-1,3-DIOXOL-6-(5AH)-ONE
4-DESMETHYLEPIPODOPHYLLOTOXIN 9-(4,6-O-ETHYLIDENE)-BETA-D-GLUCOPYRANOSIDE
4'-demethylepipodophyllotoxin-(4,6-o-(r)-ethylidene-beta-d-glucopyranoside)
4'-DEMETHYLEPIPODOPHYLLOTOXIN 9-(4,6-O-ETHYLIDENE-BETA-D-GLUCOPYRANOSIDE)
4-demethylepipodophyllotoxin-beta-d-ethylideneglucoside
Etoposide USP26
Etoposide (FDA) USP24 BP98
Etoposide BP2000
ETOPOSIDE, MM(CRM STANDARD)
ETOPOSIDE, EP STANDARD
ETOPOSIDE, USP STANDARD
ETOPOSIDE, RESOLUTION MIXTURE USP STANDARD
ETOPOSIDE, USP 99+%
Etoposide,Usp28
C29H32O13
Etoposide4-O--D-Galactopyranoside
Furo3,4:6,7naphtho2,3-d-1,3-dioxol-6(5aH)-one, 9-4,6-O-(1R)-ethylidene-.beta.-D-glucopyranosyloxy-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
4'-demethylepipodophyllotoxin 9-(4,6-o-ethylidene-β-d-glucopyranoside)
Etoposide(α-tipe)
4'-Demethyl-1-O-[4,6-O-(ethylidene)-β-D-glucopyranosyl]epipodophyllotoxin
4'-Demethylepipodophyllotoxin ethylidene-β-D-glucoside
Epipodophyllotoxin VP 16213
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-β-D-glucopyranoside (8CI)
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5α,5aβ,8aα,9β(R*)]]-
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
Toposar
trans-Etoposide
VP 16 (pharmaceutical)
VP 16-123
Zuyeyidal
Pharmaceutical
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