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CAS-Nr. | 518-75-2 |
Bezeichnung: | 3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxo-benzo(c)pyran-7-carbonsäure |
Englisch Name: | CITRININ |
Synonyma: | 3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxobenzo[c]pyran-7-carbonsure;3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxo-benzo(c)pyran-7-carbonsäure CIT;CTRO;CITRININ;Citriain;KIAA0949;ANTIMYCIN;Cytrinine;CITRININE;,(3r-trans)-;Citrinin,98% |
CBNumber: | CB3190931 |
Summenformel: | C13H14O5 |
Molgewicht: | 250.25 |
MOL-Datei: | 518-75-2.mol |
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3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxo-benzo(c)pyran-7-carbonsäure physikalisch-chemischer Eigenschaften |
Schmelzpunkt:: |
175°C (dec.) |
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3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxo-benzo(c)pyran-7-carbonsäure Chemische Eigenschaften,Einsatz,Produktion Methoden |
Chemische Eigenschaften yellow crystalline powder or flakes |
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Verwenden Antibiotic substance produced by a white spore aspergilus which has been placed under the species name Aspergillus niveus. Also produced in small quantities by Penicillium citrinum. |
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Verwenden Citrinin is a quinonemethine mycotoxin produced by diverse fungi including Aspergillus and Penicillium. Citrinin has been extensively investigate, and is a potent nephrotoxin with hepatoxic and teratogenic activity. Citrinin is the causative agent of Balkan nephropathy and yellow rice fever in humans. At the molecular level, citrinin exhibits a range of effects including free radical damage to DNA and disruption of mitochondrial membrane-bound enzymic activities and structural integrity. Specifically, citrinin is an inhibitor of NADH dehydrogenase in the mitochondrial electron transport chain and this action is responsible for recent reports of citrinin's apoptotic activity. |
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Verwenden Citrinin is a quinonemethine mycotoxin produced by diverse fungi including Aspergillus and Penicillium. Citrinin has been extensively investigated and is a potent nephrotoxin with hepatoxic and teratogenic activity. Citrinin is the causative agent of Balkan nephropathy and yellow rice fever in humans. At the molecular level, citrinin exhibits a range of effects including free radical damage to DNA and disruption of mitochondrial membrane-bound enzymic activities and structural integrity. Specifically, citrinin is an inhibitor of NADH dehydrogenase in the mitochondrial electron transport chain and this action is responsible for recent reports of citrinin's apoptotic activity. |
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R-Sätze Betriebsanweisung: R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut. R40:Verdacht auf krebserzeugende Wirkung. R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut. |
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S-Sätze Betriebsanweisung: S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren. S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen. S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen). S22:Staub nicht einatmen. S7/9:Behälter dicht geschlossen an einem gut gelüfteten Ort aufbewahren. |
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3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxo-benzo(c)pyran-7-carbonsäure Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxo-benzo(c)pyran-7-carbonsäure Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 60)Lieferanten |
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ANTIMYCIN
CIT
CITRININ
CITRININ, PENICILLIUM CITRINUM
518-75-2
4,6-DIHYDRO-8-HYDROXY-3,4,5-TRIMETHYL-6-OXO-3H-2-BENZOPYRAN-7-CARBOXYLIC
4,6-DIHYDRO-8-HYDROXY-3,4,5-TRIMETHYL-6-OXO-3H-2-BENZOPYRAN-7-CARBOXYLIC ACID
(3r,4s)-4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3h-2-benzopyran-7-carbox
(3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid
,(3r-trans)-
3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-
3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R-trans)-
4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3h-2-benzopyran-7-carboxylicaci
6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-(3r-trans)-3h-2-benzopyran-7-carboxylicaci
8-Hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-isochromene-7-carboxylic acid
Citriain
citrinin,antimycin
3,4-dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxobenzo(c)pyran-7-carboxylic acid
CITRININ FROM PENICILLIUM CITRINUM
Cytrinine
C13H14O5
3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R,4S)-
CITRININE
Active Pharmaceutical Ingredients
Antimycin, Citrinin
(3R)-3α,4β,5-Trimethyl-6-oxo-8-hydroxy-3,4-dihydro-6H-2-benzopyran-7-carboxylic acid
(3R)-4,6-Dihydro-8-hydroxy-3α,4β,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid
(3R,4S)-3,4,5-Trimethyl-6-oxo-8-hydroxy-4,6-dihydro-3H-2-benzopyran-7-carboxylic acid
Citrinin,98%
CITRININ(RG)
Citrinin,4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid
Chiral Reagents
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
antibiotic
MeleaMycin, AntiMycin, Monascidin A
Anti-CTRO antibody produced in rabbit
CTRO
KIAA0949
Rho-interacting
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