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7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat Produkt Beschreibung

CAS-Nr.22144-77-0
Bezeichnung:7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat
Englisch Name:CYTOCHALASIN D
Synonyma:7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat
Nsc209835;ZYGOSPORIN A;Lygosporin a;CYTOCHALACIND;CYTOCHALICIND;Cytohalasin d;CYTOCHALASIN D;19-trien-17-one;CYTOCHALASIN D(RG);Cytochalasin D, Zygosporin A
CBNumber:CB2672937
Summenformel:C30H37NO6
Molgewicht:507.62
MOL-Datei:22144-77-0.mol
7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 255-260°C
storage temp. : −20°C
Sicherheit
Kennzeichnung gefährlicher: T
R-Sätze:: 25-63
S-Sätze:: 36/37-45
RIDADR : UN 1544 6.1/PG 2
WGK Germany : 3
RTECS-Nr.: GZ4850000
HazardClass : 6.1(a)
PackingGroup : I

7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Powder
Verwenden
Cytochalasin D acts as an anti-hypertensive drug acting on human intestinal epithelial caco-2 cells. Also has activity in HMG-CoA reductase inhibitors used in the lowering of cholesterol. Actin inhib itor, actin polymerization inhibitor affecting cell movement, growth, phagocytosis and even secretion.
Verwenden
Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumour agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology.
Verwenden
Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumor agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology.
Allgemeine Beschreibung
Needles or fluffy white powder.
Reaktivität anzeigen
CYTOCHALASIN D may be sensitive to exposure to heat. CYTOCHALASIN D can react with strong oxidizing agents, strong acids and strong bases. .
Brandgefahr
Flash point data for CYTOCHALASIN D are not available; however, CYTOCHALASIN D is probably combustible.
R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Biologische Aktivit?t
Potent disruptor of actin filament function. Alters tight junction permeability. Unlike cytochalasin B, does not inhibit monosaccharide transport across the plasma membrane.
7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 70)Lieferanten     
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J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)sh@meryer.comCHINA 40407 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Chembest Research Laboratories Limited +86(0)21-20908456+86(0)21-58180499sales@biochembest.comCHINA 6000 61
BOC Sciences 1-631-504-60931-631-614-7828sales@bocsci.comUSA 9972 65
Dalian Meilun Biotech Co., Ltd. 0411-66771943；0411-667719420411-66771945sales@meilune.comCHINA 5010 58
BioBioPha Co., Ltd. +86-871-65217109 QQ: 1020188433+86-871-65215563y.liu@mail.biobiopha.comCHINA 2997 65
ShangHai YuanYe Biotechnology Co., Ltd. 021-61312847 qq：2797782341021-601373572797782341@qq.comCHINA 7597 60
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333021-50323701sale@aladdin-e.comCHINA 24330 65
Shanghai Tauto Biotech Co., Ltd 0086-21-513205880086-21-51320502export2@tautobiotech.comCHINA 4011 66
 
22144-77-0(7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat)Verwandte Suche:
7(S)-Hydroxy-16(R)-methyl-10-phenyl-24-oxa(14)cytochalasa-6(12),13(E),21(E)-trien-1,20,23-trion 7(S),18-Dihydroxy-16(S),18(R)-dimethyl-10-phenyl[11]cytochalasa-5,13(E),19(E)-trien-1,17-dion-21(R)-acetat 7(S),20(R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa(14)cytochalasa-6(12),13(E),21(E)-trien-1,23-dion Octahydro-6,7a-dihydroxy-4-methyl-7-[4-methyl-7-(tetrahydro-5-oxo-2-furyl)-1-heptenyl]-3-(phenylmethyl)-1H-isoindol-1-on 21,23-Dioxa(13)cytochalasa-13,19-dien-1,17,22-trion, 6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-,(7S,13E,16S,18R,19E)- 1-Hexylallylacetat 8-Octanlactam Dodec-3-en-1-al 7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-trien-1,17-dion-21(R)-acetat Valdetamid 3-Amino-2,2-dimethylpropan-1-ol
ZYGOSPORIN A CYTOCHALASIN D CYTOCHALASIN D, ZYGOSPORIUM MANSONII CYTOCHALASIN D, ZYGUSPORIUM MANSONII 22144-77-0 BioChemical Antibiotics Antibiotics A to Z Antibiotics A-F (7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE (11)cytochalasa-6(12),13,19-triene-1,17-dione,21-(acetyloxy)-7,18-dihydroxy-16 ,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-,15-acetate ,18-dimethyl-10-phenyl-,(7s,13e,16s,18r,19e,21r)- 15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-115-acetate 19-trien-17-one 1h-cycloundec(d)isoindole-1,11(2h)-dione,3-benzyl-3,3-alpha,4,5,6,6-alpha,9,10 1h-cycloundec(d)isoindole-1,11(2h)-dione,3-benzyl-3,3-alpha4,5,6,6-alpha,9,10, 7,18-dihydroxy-10-phenyl-5,16,18-trimethyl-[11]cytochalas-21-acetoxy-6(12),13, cytochalasin D from zygosporium masonii 7(S),18(R)-dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-triene-1,17-dione 21(R)-acetate CYTOCHALASIN D FROM ZYGOSPORIUMMANSONII 1H-Cycloundecdisoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)- CYTOCHALASIN D(RG) CYTOCHALACIND CYTOCHALICIND Cytochalasin D, Zygosporin A Caspases/Apoptosis (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione [11]Cytochalasa-6(12),13,19-triene-1,17-dione, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E,21R)- [11]Cytochalasa-6[12],13,19-triene-1,17-dione, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl- 1H-Cycloundec[D]isoindole-1,11(2H)-dione, 3-benzyl-3,3-.alpha.,4,5,6,6-.alpha.,9,10,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-, 15-acetate Cytohalasin d Lygosporin a Nsc209835 antibiotic
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