| Identification | More | 【Name】
Dexamethasone | 【CAS】
50-02-2 | 【Synonyms】
(11B,16A)-9-FLUORO-11,17,21-TRIHYDROXY-16-METHYL-PREGNA-1,4-DIENE-3,20-DIONE
(11BETA,16ALPHA)-9-FLUORO-11,17,21-TRIHYDROXY-16-METHYLPREGNA-1,4-DIENE-3,20-DIONE
1,4-PREGNADIEN-9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE
1,4-PREGNADIEN-9ALPHA-FLUORO-16ALPHA-METHYL-11BETA, 17ALPHA, 21-TRIOL 3,20-DIONE
1,4-PREGNADIENE-3,20-DIONE-9ALPHA-FLUORO-16ALPHA METHYL-11BETA,17ALPHA,21-TRIOL
9ALPHA-FLUORO-11BETA,17,21-TRIHYDROXY-16ALPHA-METHYL-1,4-PREGNADIENE 3,20DIONE
9ALPHA-FLUORO-11BETA,17ALPHA,21-TRIHYDROXY-16ALPHA-METHYLPREGN-1,4-DIENE-3,20-DIONE
9ALPHA-FLUORO-16ALPHA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE
9ALPHA-FLUORO-16ALPHA-METHYLPREDNISOLONE
CALONAT
DECACORTIN
DECADRON
DECASONE
DERONIL
DEXAMETHASON
DEXAMETHASONE
DEXAMETHASONE BASE
DEXAMETHASONUM
HEXADECADROL
PREDNISOLONE F | 【EINECS(EC#)】
200-003-9 | 【Molecular Formula】
C22H29FO5 | 【MDL Number】
MFCD00064136 | 【Molecular Weight】
392.46 | 【MOL File】
50-02-2.mol |
| Chemical Properties | Back Directory | 【Appearance】
White Crystalline Solid | 【mp 】
262-264 °C(lit.)
| 【alpha 】
75 º (c=1, dioxane) | 【refractive index 】
76 ° (C=1, Dioxane) | 【storage temp. 】
2-8°C
| 【solubility 】
ethanol: 1 mg/mL
| 【form 】
powder
| 【color 】
off-white
| 【Stability:】
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive. | 【Water Solubility 】
10 mg/100 mL (25 ºC) | 【Usage】
A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase | 【Merck 】
14,2943 | 【BRN 】
2066651 | 【CAS DataBase Reference】
50-02-2(CAS DataBase Reference) | 【NIST Chemistry Reference】
Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2) | 【EPA Substance Registry System】
50-02-2(EPA Substance) |
| Safety Data | Back Directory | 【Hazard Codes 】
Xi,Xn | 【Risk Statements 】
R43:May cause sensitization by skin contact.
R40:Limited evidence of a carcinogenic effect.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | 【Safety Statements 】
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S22:Do not breathe dust . | 【WGK Germany 】
2
| 【RTECS 】
TU3980000
| 【Hazardous Substances Data】
50-02-2(Hazardous Substances Data) |
| Hazard Information | Back Directory | 【General Description】
Odorless white to off-white crystalline powder with a slightly bitter taste. | 【Reactivity Profile】
DEXAMETHAZONE(50-02-2) may be sensitive to prolonged exposure to light. This chemical is incompatible with strong oxidizers, strong acids, acid chlorides and acid anhydrides. Oxidation may occur with bases. | 【Air & Water Reactions】
Insoluble in water. | 【Fire Hazard】
Flash point data for this chemical are not available; however, DEXAMETHAZONE is probably combustible. |
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