| Identification | More | 【Name】
Hydroxyurea | 【CAS】
127-07-1 | 【Synonyms】
DROXIA
HYDROXYCARBAMIDE
HYDROXYUREA
N-HYDROXYUREA
biosupressin
carbamohydroxamicacid
carbamohydroxyamicacid
Carbamoylhydroxylamine
carbamoyloxime
carbamylhydroxamate
hidrix
hu
hydrea
hydreia
hydroxycarbamine
hydroxyharnstoff
hydroxylurea
hydroxy-ure
hydroxyurea(d4)
hydura | 【EINECS(EC#)】
204-821-7 | 【Molecular Formula】
CH4N2O2 | 【MDL Number】
MFCD00007943 | 【Molecular Weight】
76.05 | 【MOL File】
127-07-1.mol |
| Chemical Properties | Back Directory | 【Appearance】
Off-White Crystalline Solid | 【mp 】
135-140 °C
| 【storage temp. 】
2-8°C
| 【solubility 】
H2O: 50 mg/mL
| 【form 】
powder
| 【color 】
white
| 【Water Solubility 】
soluble | 【Usage】
An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydro | 【Merck 】
14,4848 | 【BRN 】
1741548 | 【CAS DataBase Reference】
127-07-1(CAS DataBase Reference) | 【EPA Substance Registry System】
127-07-1(EPA Substance) |
| Safety Data | Back Directory | 【Hazard Codes 】
T,Xn | 【Risk Statements 】
R63:Possible risk of harm to the unborn child.
R61:May cause harm to the unborn child.
R40:Limited evidence of a carcinogenic effect. | 【Safety Statements 】
S53:Avoid exposure - obtain special instruction before use .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | 【RIDADR 】
2811 | 【WGK Germany 】
3
| 【RTECS 】
YT4900000
| 【Hazard Note 】
Toxic | 【PackingGroup 】
III | 【Hazardous Substances Data】
127-07-1(Hazardous Substances Data) |
| Hazard Information | Back Directory | 【General Description】
Odorless or almost odorless white to off-white crystalline solid. Tasteless. | 【Reactivity Profile】
An amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). | 【Air & Water Reactions】
Water soluble. | 【Fire Hazard】
Flash point data for this chemical are not available; however, HYDROXYUREA is probably combustible. |
|
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