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ChemicalBook >> CAS DataBase List >> 3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one

3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one

CAS No.138402-11-6
Chemical Name:3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one
Synonyms:AVAPRO;APROVEL;SR-47436;Irbesarta;Irbesatan;BMS-186295;IRBESARTAN;Lrbesartan;Irbersartan;Irbesartan(Avapro)
CBNumber:CB4454663
Molecular Formula:C25H28N6O
Formula Weight:428.53
MOL File:138402-11-6.mol
3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one Property
mp : 180-181°C
storage temp. : -20°C Freezer
CAS DataBase Reference: 138402-11-6(CAS DataBase Reference)
Safety
Hazard Codes : Xn
Risk Statements : 22
Safety Statements : 26

3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one Chemical Properties,Usage,Production

Chemical Properties
Crystalline Solid
Usage
An angiotensin II type 1 (AII1)-receptor antagonist
Usage
antidepressant
Usage
For the treatment of hypertension, as well as diabetic nephropathy with an elevated serum creatinine and proteinuria (>300 mg/day) in patients with type 2 diabetes and hypertension. Irbesartan is also used as a second line agent in the treatment of conges
3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one Preparation Products And Raw materials
Raw materials
3-METHOXYPROPIONIC ACID Triethyl orthobutyrate Sodium azide ORTHO-N-VALERIC ACID TRIETHYL ESTER Fluorene Tetrazole Benzylamine
Preparation Products
3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one Suppliers      Global( 253)Suppliers     
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138402-11-6(3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one)Related Search:
2-butyl-1,3-biazaspiro[4,4]-non-1-ene-4-one hydrochloride (intermediate of Irbesartan) Irbesartan Tablets Irbesartan13 IRBESARTAN-D4 IRBESARTAN (GMP) Irbesartan N--D-Glucuronide intermediate of irbesartan 4-bromomethyl-2-(1-triphenylmethyltetrazole-5-yl)biphenyl (intermediate of Irbesartan) 2-n-butyl-l,3-diazaspiro[4,4]non-l-ene-4-one(for Irbesartan) Irbesartan2-(4-AminomethylPhenyl)Benzonitrile 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile 2n-butyl-4-spirocyclopentane-2-imidazoline-5-one hydrochloride (intermediate of irbesartan),2-N-BUTYL-1,3-DIAZA-SPIRO[4,4]NON-1-EN-4-ONE HYDROCHLORIDE (INTERMEDIATE OF IRBESARTAN) Irbesartan Related Compound A IRBESARTAN Irbesartan, Crude IRBESARTAN-D3 TRIPHENYL IRBESARTAN,TRITYL IRBESARTAN,TRIPHENYLMETHYL IRBESARTAN,2-butyl-3-[[4-[2-(2-trityl-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one 3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one
3-butyl-2-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one 138402-11-6 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE IRBESARTAN BMS-186295 AVAPRO APROVEL SR-47436 Lrbesartan 2N-Butyl-4-spirocyclopentane-2-imidazolin-5-one hydrochloride IrbesartanC25H28N6O C25H28N6O 2-N-BUTYL-4-SPIROCYCLOPENTANE-1-[(2-CYANOBIPHENYL-4-YL)METHYL]-2-IMIDAZOLIN-5-ONE 2-Butyl-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, BMS-186295, SR-47436, Aprovel, Avapro IRBESARTAN/3-BYTY1-3-[P-(0-1H-TETRAZOL-5-Y1-PHENY1)BENZY1],3-DIAZOSPIRO[4,4]NON-1-EN-4-KETONE 2-N-BUTYL-4-SPIROCYCLOPENTANE-1-[(2-CYANOBIPHENYL-4-YL)METHYL]-2-IMIDAZOLIN-5-ONE(IRBESARTAN) 2-buty1-3-[p-(0-1H-tetrazol-5-y1-pheny1)benzy1]1,3-diazospiro[4,4]non-1-en-4-ketone 42854 Active Pharmaceutical Ingredients Antihypertensive Irbersartan 2-BUTYL-3-[2''-(1H-TETRAZOL-5-YL)BIPHENYL-4-YLMETHYL]1,3-DIAZA-SPIRO[4.4]NON-1-EN-4-ONE 2-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4- Irbesarta Hypertension C25H28ON6 Inhibitors Intermediates & Fine Chemicals Pharmaceuticals API's 2-Butyl-3-[[2’-(1H-tetrazol-5-y1)[1，l'-biphenyl]-4-y1]methyl]-1，3-diazaspiro[4.4]non-1-en-4-one 1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- 2-Isopropryl-4-methylthiazole 2-butyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one 2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one 2-butyl-3-[4-[2-(2H-tetrazol-5-yl)phenyl]benzyl]-1,3-diazaspiro[4.4]non-1-en-4-one 2-Isopropryl-4-methylthiazole (Irbesartan) Irbesartan (200 mg) Aromatics Heterocycles Irbesartan(Avapro) 2-butyl-3-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}Methyl)-1,3-diazaspiro[4.4]non-1-en-4-one 3-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one 3-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one Irbesatan Isotopically Labeled Pharmaceutical Reference Standard LITAREX Irbesartan Synonyms 3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
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